Antifungals Flashcards
(16 cards)
Lotrimin
Generic Name: Clotrimazole
Class: Azole
Indications: Fungal Infection
Special Considerations: *
Dosage Forms: Oral solid; topical; vaginal
Jublia
Generic Name: Efinaconazole
Class: Azole
Indications: Fungal infections
Special Considerations: Flammable med
Dosage Forms: Topical
Diflucan
Generic Name: Fluconazole
Class: Azole
Indications: Fungal infection
Special Considerations: *; Interacts with many meds (atorvastatin, erythromycin, phenytoin, etc.); NIOSH med; Should be avoided in pregnant patients
Dosage Forms: Injectable; Oral powder for suspension; Oral solid
Sporanox
Generic Name: Itraconazole
Class: Azole
Indications: Fungal Infection
Special Considerations: *; Avoid in heart failure patients (BW); Interacts with many meds (felodipine, methadone, ticagrelor, etc.); Should be taken with a full meal
Dosage Forms: Oral liquid; oral solid
Nizoral
Generic Name: Ketoconazole
Class: Azole
Indications: Fungal infection
Special Considerations: *; Interacts with many meds (alprazolam, methadone, simvastatin, ets. with oral solid); Patients should avoid alcohol with oral form
Dosage Forms: Oral solid; Topical
Monistat
Generic Name: Miconazole
Class: Azole
Indications: Fungal infection
Special Considerations: Avoid buccal dosage form in patients with a milk protein allergy
Dosage Forms: Oral solid; Topical; Vaginal
Vfend
Generic Name: Voriconazole
Class: Azole
Indications: Fungal infections
Special Considerations: Interacts with many meds (alprazolam, simvastatin, etc.); LFTs will be monitored (with prolonged use); Should take on an empty stomach (tab, cap)
Dosage Forms: Injectable; oral solid for suspension; oral solid
Ambisome
Generic Name: Amphotericin B
Class: Polyenes
Indications: Fungal infection
Special Considerations: High-alert med; Interacts with aminoglycosides (gentamicin, tobramycin, etc); May cause allergic reactions; SCr and BUN will be monitored
Dosage Forms: Injectable
Mycostatin
Generic Name: Nystatin
Class: Polyenes
Indications: Fungal infections
Special Considerations: Should be used with caution in patients allergic to parabens (with oral suspension and topical form)
Dosage Forms: Oral liquid; Oral solid; topical
Lamisil
Generic Name: Terbinafine
Class: Allylamine
Indications: Fungal infection
Special Considerations: LFTs will be monitored (with oral dosage form); Patients with liver disease should avoid taking oral solid form
Dosage Forms: Oral solid; Topical
Cancidas
Generic Name: Caspfungin
Class: Echinocandins
Indications: Fungal infection
Special Considerations: Administer alone in IV line; Interacts with many meds (carbamazepine, phenytoin, etc)
Dosage Forms: Injectable
Kerydin
Generic Name: Tavaborole
Class: Ozaborole
Indications: Fungal infection
Special Considerations: Flammable med
Dosage Forms: Topical
Loprox
Generic Name: Ciclopirox
Class: Misc. Antifungal
Indications: Fungal infection
Special Considerations: Lacquer topical form is flammable
Dosage Forms: Topical
Lotrisone
Generic Name: Clotrimazole/ betamethasone
Class: Clotrimazole (azole); Betamethasone (corticosteroid)
Indications: Fungal infection
Special Considerations: LFTs may be monitored (with prolonged therapy of oral dosage form); Excessive use can lead to impaired wound healing and skin thinning; May cause drying and irritation at application site (increased with augmented dosage form)
Dosage Forms: Topical
Mycolog II
Generic Name: Nystatin/ triamcinolone
Class: Nystatin (polyene); Triamcinolone (corticosteroid)
Indications: Fungal infection
Special Considerations: Should be used with caution in patients allergic to parabens (with oral suspension and topical form); Excessive use can lead to impaired would healing and skin thinning; May cause drying and irritation at application site (with topical form)
Dosage Forms: Topical
Azoles common special considerations *
LFTs may be monitored (with prolonged therapy of oral dosage form)
