Antifungals Flashcards

1
Q

Name the 3 kinds of fungi

A

Yeast
Mould
Dimorphic

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2
Q

Name yeasts

A

Candida spp

Cryptococcus neoformans

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3
Q

Name moulds

A
Aspergillus fumigatus
Aspergillus flavus
Aspergillus niger
Aspergillus terreus
Mucor spp
Fusarium spp
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4
Q

Name dimorphic fungi

A

Histoplasma capsulatum
Blastomyces dermatitis
Coccidioides immitis
Sporothrix shenkii

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5
Q

Which antifungals work on the cell membrane?

A

Polyenes

  • amphotericin B
  • lipid AmB
  • nystatin
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6
Q

Which antifungals work on the cell wall?

A

Echinocandins

  • caspofungin
  • micafungin
  • anidulafungin
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7
Q

Which antifungals work on the cytoplasm?

A

Azoles

  • fluconazole
  • ketoconazole
  • itraconazole
  • voriconazole
  • posaconazole
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8
Q

Which antifungals work on the DNA?

A

Antimetabolites

- 5-fluorocytosine

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9
Q

Name side effects of amphotericin B

A

Nephrotoxemia
Acute reaction
Phlebitis

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