Antigen Determinant Flashcards
Revision (4 cards)
Ag Determinants
Antigenic determinants, also known as epitopes, are specific regions on the surface of an antigen that are recognized and bound by antibodies or T-cell receptors.
Each antigen can have multiple epitopes, allowing the immune system to target it in different ways.
3 Ag Determinant
Isotype
Idiotype
Allotype
Isotype
Isotypes determine the functional properties of the antibody and its role in the immune response.
The five main isotypes in humans are:
IgG
IgA
IgM
IgE
IgD
Each isotype has a unique role in the immune system, such as neutralizing pathogens, activating complement, or mediating allergic reactions.
Idiotype`
These unique determinants (epitopes) define the antibody’s ability to recognize and bind to a specific antigen. The idiotype is different for each antibody, even if the antibodies belong to the same isotype.