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Chapter 17: Raskin & Meyer > Antigen Markers, Sources, Tissue Controls, & Uses for Antibodies Used in Dogs/Cats > Flashcards

Antigen Markers, Sources, Tissue Controls, & Uses for Antibodies Used in Dogs/Cats Flashcards

1
Q

What is the tissue control & use for the actin muscle antigen in dogs?

A
  • skeletal muscle/heart

- muscle neoplasms

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2
Q

What is the tissue control & use for the actin sarcomeric antigen in dogs?

A
  • skeletal muscle/heart

- striated muscle tumors

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3
Q

What is the tissue control & use for the actin smooth muscle antigen in dogs?

A
  • stomach/intestine

- smooth muscle tumors

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4
Q

What is the tissue control & use for the adenovirus antigen in dogs?

A
  • infected tissue

- infection

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5
Q

What is the tissue control & use for the amylin (IAPP) antigen in cats & dogs?

A
  • pancreas

- pancreatic islet amyloid

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6
Q

What is the tissue control & use for the Bcl-2 oncoprotein antigen in cats?

A
  • lymphoid tissue

- lymphoid tumors

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7
Q

What is the tissue control & use for the B-lymphocyte antigen (BLA.36) in cats & dogs?

A
  • lymph node, spleen

- B-cell, histiocytic tumors

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8
Q

What is the tissue control & use for the CD1c (ICC) antigen in dogs?

A
  • lymphoid tissue

- dendritic cell tumors

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9
Q

What is the tissue control & use for the CD3 (ICC) antigen in dogs?

A
  • lymph node, spleen

- T-cell lymphoma

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10
Q

What is the tissue control & use for the CD3 epsilon (IHC) antigen in cats & dogs?

A
  • lymph node, spleen

- T-cell lymphoma

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11
Q

What is the tissue control & use for the CD10 (CALLA antigen) in dogs?

A
  • kidney

- renal, stromal tumors

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12
Q

What is the tissue control & use for the CD11d (IHC) antigen in dogs?

A
  • spleen

- lymphoid, histiocytic tumors

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13
Q

What is the tissue control & use for the CD11d (ICC) antigen in cats & dogs?

A
  • spleen

- lymphoid, histiocytic tumors

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14
Q

What is the tissue control & use for the CD18 antigen in cats?

A
  • spleen

- leukocytic tumors

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15
Q

What is the tissue control & use for the CD18 antigen in dogs?

A
  • spleen, lymph node

- leukocytic tumors

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16
Q

What is the tissue control & use for the CD20 antigen in cats & dogs?

A
  • spleen, lymph node

- B-cell tumors

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17
Q

What is the tissue control & use for the CD31 antigen in dogs?

A
  • skin, other

- vascular endothelial & megakaryocytic tumors

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18
Q

What is the tissue control & use for the CD45 antigen in dogs?

A
  • spleen, lymph node

- leukocytic tumors

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19
Q

What is the tissue control & use for the CD45RA antigen in dogs?

A
  • lymphoid tissue

- lymphoid tumors

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20
Q

What is the tissue control & use for the CD79a antigen in cats & dogs?

A
  • lymph node, spleen

- B-cell lymphoma

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21
Q

What is the tissue control & use for the CD117 (c-Kit protein) antigen in dogs?

A
  • mast cell tumor

- mast cell tumor

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22
Q

What is the tissue control & use for the calcitonin antigen in cats & dogs?

A
  • thyroid

- C-cell tumors

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23
Q

What is the tissue control & use for the calponin antigen in dogs?

A
  • small intestine, stomach

- smooth muscle & myoepithelial tumors

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24
Q

What is the tissue control & use for the calretinin antigen in cats & dogs?

A
  • kidney

- renal tubules, nerve tissue, adrenocortical tumors, mesothelioma

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25
What is the tissue control & use for the canine distemper virus antigen in dogs?
- infected tissue | - infection
26
What is the tissue control & use for the carcinoembryonic antigen in dogs?
- intestine | - epithelial tumors
27
What is the tissue control & use for the caspase-3 antigen in dogs?
- lymph node | - apoptotic cells
28
What is the tissue control & use for the chromogranins A & B antigen in dogs?
- pancreas | - neuroendocrine tumor
29
What is the tissue control & use for the coronavirus antigen in cats & dogs?
- infected tissue | - infection
30
What is the tissue control & use for the COX-1 antigen in dogs?
- normal urinary bladder | - normal urothelium, endothelium
31
What is the tissue control & use for the COX-2 antigen in cats & dogs?
- transitional cell carcinoma | - carcinomas
32
What is the tissue control & use for the cytokeratin 5 antigen in dogs?
- mammary gland, skin | - myoepithelium, basal cells
33
What is the tissue control & use for the cytokeratin 7 antigen in dogs?
- skin, urinary bladder | - glandular epithelium
34
What is the tissue control & use for the cytokeratins 8/18 antigen in dogs?
- liver, stomach | - glandular epithelium
35
What is the tissue control & use for the cytokeratins AE1-AE3 antigen in cats & dogs?
- skin | - general epithelium marker
36
What is the tissue control & use for the cytokeratins Pan antigen in dogs?
- glandular/squamous epithelium | - general epithelium marker
37
What is the tissue control & use for the cytokeratins HMW antigen in dogs?
- skin | - squamous epithelium, mesothelium, hepatocytes
38
What is the tissue control & use for the desmin antigen in dogs?
- skin, stomach, intestine | - muscle tumors
39
What is the tissue control & use for the E-cadherin antigen in dogs?
- skin | - Langerhan's cells, epithelium, histiocytoma, meningiomas
40
What is the tissue control & use for the estrogen receptor alpha in cats & dogs?
- uterus | - estrogen receptor tumors
41
What is the tissue control & use for the factor VIII-related antigen in dogs?
- skin, other | - vascular endothelial & megakaryocytic tumors
42
What is the tissue control & use for the feline calcivirus antigen in cats?
- infected tissue | - infection
43
What is the tissue control & use for the feline herpesvirus 1 antigen in cats?
- infected tissue | - infection
44
What is the tissue control & use for the feline leukemia virus antigen in cats?
- infected tissue | - infection
45
What is the tissue control & use for the glial fibrillary acidic protein antigen in dogs?
- brain | - neural (glial) tumors
46
What is the tissue control & use for the glucagon antigen in cats & dogs?
- pancreas | - glucagon-producing tumors
47
What is the tissue control & use for the Glut-1 antigen in dogs?
- peripheral nerve | - peripheral nerves, stromal cells, kidney
48
What is the tissue control & use for the hepatocyte marker-1 (Hep Par 1) antigen in dogs?
- liver | - hepatocellular tumors
49
What is the tissue control & use for the Ig kappa chains antigen in dogs?
- lymph node | - plasmacytomas
50
What is the tissue control & use for the Ig lambda chains antigen in dogs?
- lymph node | - plasmacytomas
51
What is the tissue control & use for the immunoglobulin M antigen in cats & dogs?
- lymph node | - lymphoid tumors
52
What is the tissue control & use for the inhibin-alpha antigen in dogs?
- testicle, Sertoli cell tumor | - sex cord - stromal & adrenal cortical tumors
53
What is the tissue control & use for the insulin antigen in dogs?
- pancreas | - insulin-producing tumors
54
What is the tissue control & use for the Ki-67 antigen in dogs?
- lymphoma | - cell proliferation marker
55
What is the tissue control & use for the laminin antigen marker in cats & dogs?
- skin/kidney | - perivascular wall tumors & basement membrane
56
What is the tissue control & use for the Leptospira antigen in dogs?
- infected tissue | - infection
57
What is the tissue control & use for the lysozyme antigen in cats & dogs?
- liver, spleen | - histiocytes
58
What is the tissue control & use for the Melan A antigen in cats & dogs?
- melanoma | - melanomas, steroid-producing tumors
59
What is the tissue control & use for the MHC II antigen in dogs?
- histioyctoma, lymph node | - antigen presenting cells, lymphocytes
60
What is the tissue control & use for the microphthalmia transcription factor antigen in dogs?
- melanoma | - melanomas
61
What is the tissue control & use for the MUM 1 protein antigen in dogs?
- plasmacytoma | - plasmacytomas, myelomas, some B-cell tumors
62
What is the tissue control & use for the myeloid/histiocytic antigen in dogs?
- spleen, liver | - macrophages, myeloid cells
63
What is the tissue control & use for the myoglobin antigen in dogs?
- skeletal muscle, heart | - skeletal muscle tumors
64
What is the tissue control & use for the Neospora caninum antigen in dogs?
- infected tissue | - infection
65
What is the tissue control & use for the nerve growth factor receptor antigen in dogs?
- nerve | - nerves
66
What is the tissue control & use for the neurofilament-2 antigen in dogs?
- brain | - neuron neurofilaments
67
What is the tissue control & use for the neuron specific enolase antigen in dogs?
- pancreas | - neuroendocrine marker
68
What is the tissue control & use for the OCT3/4 antigen in dogs?
- mast cell tumor | - germ cell & mast cell tumors
69
What is the tissue control & use for the p63 antigen in dogs?
- skin, mammary gland | - myoepithelium, basal cells
70
What is the tissue control & use for the papilloma virus in dogs?
- infected tissue | - infection
71
What is the tissue control & use for the parathyroid hormone antigen in dogs?
- parathyroid | - normal & neoplastic parathryoid
72
What is the tissue control & use for the parvovirus antigen in dogs?
- infected tissue | - infection
73
What is the tissue control & use for the progesterone receptor antigen in dogs?
- uterus | - progesterone receptor tumors
74
What is the tissue control & use for the proliferating cell nuclear antigen in dogs?
- lymphoma, lymph node | - proliferation marker
75
What is the tissue control & use for the Protein Gene Product 9.5 antigen in cats & dogs?
- adrenal gland | - neuroendocrine marker
76
What is the tissue control & use for the S-100 protein antigen in cats & dogs?
- nerve, brain | - neural marker, neuroendocrine tumors
77
What is the tissue control & use for the somatostatin antigen in dogs?
- pancreas | - pancreatic islet tumors, some carcinoids
78
What is the tissue control & use for the synaptophysin antigen in dogs?
- pancreas | - neuroendocrine marker
79
What is the tissue control & use for the thyroglobulin antigen in cats & dogs?
- thyroid | - thyroglobulin-producing tumors
80
What is the tissue control & use for the thyroid transcription factor-1 antigen in dogs?
- lung, thyroid | - lung & thyroid neoplasms
81
What is the tissue control & use for the Toxoplasma gondii antigeni in cats?
- infected tissue | - infection
82
What is the tissue control & use for the tryptase antigen in dogs?
- mast cell tumor | - mast cell tumors
83
What is the tissue control & use for the uroplakin III antigen in dogs?
- urinary bladder | - urothelial neoplasms
84
What is the tissue control & use for the vimentin antigen in dogs?
- skin, stomach | - mesenchymal tumor marker

Chapter 17: Raskin & Meyer (6 decks)

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