Antigen Qs 11-20

Question 1

Immunogenicity:

Answer 1

Is not a property of haptens

Question 2

Lymphocytes are activated by antigen in the:

Answer 2

Lymph nodes

Question 3

A molecule that can be covalently linked to a non-immunogenic antigen to make it an immunogen is called a:

Answer 3

Carrier

Question 4

A polyclonal antibody response:

Answer 4

Is produced by several B cells recognizing different epitopes on the same antigen.

Question 5

Very low doses of antigen may induce:

Answer 5

Low zone tolerance

Question 6

A virus vaccine that can activate cytotoxic T cells must contain:

Answer 6

Live virus

Question 7

Which statement about antigen epitopes is FALSE?

Answer 7

B cells bind only processed antigen epitopes.

Question 8

CD antigens:
(cluster of differentiation = CD)

Answer 8

Function as receptors for cytokine and CAMs

Question 9

A patient desperately needs a bone marrow transplant, and a perfect match cannot be found. The rejection response in unmatched marrow is primarily due to the presence of mature T cells that recognize the recipient’s cells as foreign. To minimize this rejection response, the marrow can be treated before transfusion into the recipient with complement plus antibody to human:

Answer 9

CD3

Question 10

Antibody to membrane receptors sometimes inhibits receptor function and sometimes mimics the action of the normal receptor ligand. An antibody which should NOT either block of stimulate B cell function would be anti-:

Answer 10

CD56