AntiHYPOtensive agents

Question 1

What is the ACTION of hypotensive agents?

Answer 1

• stimulate all adrenergic receptors/ SNS
• Heart rate and myocardial contractility increases
• blood vessels constrict and BP increase
• bronchi dilate and rate/depth of breathing increases

Question 2

What are antihypotensive agents?

Answer 2

VASOPRESSORS
sympathomimetics
sympathetic adrenergic agonists
alpha and beta adrenergic agonists

Question 3

CONTRINDICATIONS / CAUTIONS

antihypotensive agents

Answer 3

Do not take if allergic
If you have:
tachyarrhythmias / ventricular fibrillation
hypovolemia (decrease volume of circulating blood in body)
phenochromocytoma (type of neuroendocrine tumor)

Question 4

Reason / indication for taking Antihypotensive agents

Answer 4

HYPOTENSIVE STATES
---shock
---heart failure
ANAPHYLAXIS
BRONCHOSPASM
ASTHMA

Question 5

Name some hypotensive meds

Answer 5

Dopamine and Dobutamine

Epinephrine and Norepinephrine

(IV MEDS)

Question 6

Antihypotensive meds

DRUG DRUG interaction

Answer 6

anything like caffeine
(Ma huang / guarana /caffeine)

cold medicine

Question 7

Antihypotensive CARDIOVASCULAR

Adverse effects

Answer 7

arrhythmias
hypertension
angina
SOB
dyspena

Question 8

Antihypotensive agents GI

adverse effects

Answer 8

nausea, vomiting, constipation (due to depressant effect on GI tract)

Question 9

Antihypotensive CNS

adverse effects

Answer 9

headache, sweating, anxiety, piloerection (hairs stand up) this is related to sympathetic stimulation

Question 10

Antihypotensive adverse effect

Answer 10

HYPOKALEMIA
(low potassium)
this is because aldosterone is released

Question 11

HYPOTENSION definition

Answer 11

when heart muscle is damaged and unable to pump effectively

happens with severe blood/fluid loss

when there is extreme stress and the body’s levels of norepinephrine are depleted, leaving the body unable to respond to stimuli to raise blood pressure