Antimicrobial

Question 1

What are the 4 broad categories of B lactams

Answer 1

Penicillin, Cephalosporins, Carbapenems, and monobactams

Question 2

What are the categories of penicillin?

Answer 2

Gen 1 (Penicillin G, penicillin V)
Anti-staphlococcal penicillin
Aminopenicillin
Anti-pneumonial penicillin

Question 3

What is the Mechanism of Action of Beta Lactams?

Answer 3

1. inhibits transpeptidase
2. stimulates production of bacterial autolysins with normal remodel the bacterial cell wall

Question 4

what is the mechanism of action of Vancomycin?

Answer 4

binds to peptide chain, preventing transpeptidases from binding

Question 5

what is the mechanism of action of bacitracin

Answer 5

can’t recycle lipid carrier

Question 6

what is the mechanism of action of polymixin?

Answer 6

increases cell membrane permeability

Question 7

what are the types of polymixin?

Answer 7

Polysporin, polytrim, neosporin

Question 8

what is polysporin made of?

Answer 8

polymyxin and B+ bacitracin

Question 9

what is polytrim made of

Answer 9

Polymixin and B+ trimethoprim

Question 10

what is neosporin made of?

Answer 10

Polymixin+ Bacitracin+ neomycin

Question 11

What is the drug of choice for Syphillis/ treponium palladium?

Answer 11

Gen 1 penicillins

Question 12

What type of bacteria does Gen 1 penicillin mostly treat?

Answer 12

Gram positive but some gram negative if small enough like neisseria gonorrhea

Question 13

What type of bacteria does anti staphylococcal mostly treat?

Answer 13

not effective against gram negative

mostly effective against gram positive

Question 14

What type of drug stimulates warfarin metabolism?

Answer 14

anti-staphlococcal penicillin

Question 15

What type of bacteria does aminopenicillin mostly treat?

Answer 15

increased activity against gram negative

Question 16

What type of bacteria does antipseudomonal mostly treat?

Answer 16

Gram negative

Question 17

which type of penicillin is susceptible to bacterial B lactamase

Answer 17

1st or 2nd Generation Penicillin

Question 18

What are the specific drugs of first generation Penicillin?

Answer 18

Penicillin G and Penicillin V

Question 19

which type of penicillin is not susceptible to bacterial b lactamase

Answer 19

Antistaphlylococcal

Question 20

What are the specific drugs of Antistaphylococcal Penicillin?

Answer 20

Methicillin
Dicloxacillin

Question 21

What are the specific drugs of aminopenicillin?

Answer 21

Ampicillin
amoxicillin
augmentin (Amoxicilin + clavulanic acid)

Question 22

What are the specific drugs of first gen cephalosporin?

Answer 22

cefazolin
cephalexin

Question 23

What are the specific drugs of second gen cephalosporin?

Answer 23

Cefuroxime
cefoxitin

Question 24

What are the specific drugs of third gen cephalosporin?

Answer 24

Cefixime
ceftriaxone
ceftazidime

Question 25

What are the specific drugs of cebapenems?

Answer 25

Imipenem

Question 26

What is the order of cephalosporin generations that is effective against gram positive

Answer 26

1>2>3

Question 27

What is the order of cephalosporin generations that is effective against gram negative

Answer 27

3>2>1

Question 28

What is effective against MRSA?

Answer 28

Gen 5 Cephalosporin vancomycin (DOC)

Question 29

What type of bacteria is monobactams effective against?

Answer 29

gram negative

Question 30

what is type of bacteria is vancomycin effective against?

Answer 30

gram positive

Question 31

what is type of bacteria is bacitracin effective against?

Answer 31

gram positive

Question 32

what is type of bacteria is polymixin effective against?

Answer 32

gram -

Question 33

what is the drug of choice for C. Diff

Answer 33

vancomycin

Question 34

`what treats surgical wounds?

Answer 34

bactracin

Question 35

what treats conjunctival and lid infections?

Answer 35

Polymixin

Question 36

What drugs produce stevens-johnson syndome?

Answer 36

penicillin

Question 37

which drug class have cross reactivity between penicillin?

Answer 37

cephalosporins

Question 38

what is used as an alternative for patients who have anaphylaxis with other B lactams?

Answer 38

monobactams

Question 39

what is vancomycin's adverse reaction?

Answer 39

red man ototoxicity nephrotoxicity

Question 40

what drug should be taken on an empty stomach?

Answer 40

antistaphlococcal

Question 41

what is the most common prescribed antimicrobial

Answer 41

amoxicillin

Question 42

Which antimicrobial has love GI side effects?

Answer 42

Augementin

Question 43

what drugs have nephrotoxicity as a side effect

Answer 43

Polymixin B bacitracin vancomycin

Question 44

What treats blepharitis?

Answer 44

bacitracin

Question 45

Wat treats preseptal cellulitis

Answer 45

Amoxicillin and augmentin

Question 46

what treats orbital cellulitis

Answer 46

Third generation cephalosporin