Antimicrobial Chemotherapy

Question 1

Which antibiotic can inhibit peptidoglycan synthesis?

a) penicillin
b) erythromycin
c) ciprofloxacin

Answer 1

a)penicillin

Question 2

Name 2 glycopeptides

Answer 2

vancomycin and teicoplanin

Question 3

Which antibiotic is commonly known to cause C. diff

a) gentamicin
b) daptomycin
c) cephalosporins

Answer 3

Cephalosporins

Question 4

What do glycopeptides target?

a) protein synthesis
b) assembly of peptidoglycan precursor
c) purine synthesis

Answer 4

b)assembly of peptidoglycan precursor

Question 5

Which gram positive cocci is resistant against gentamicin?

Answer 5

streptococcus

Question 6

What do macrolides and tetracylines target?

a) peptidoglycan synthesis
b) DNA synthesis
c) protein synthesis

Answer 6

c)protein synthesis

Question 7

What 5 antibiotic classes target protein synthesis?

Answer 7

aminoglycosides
macrolides
tetracyclines
oxazolidinone
cyclic lipopeptide

Question 8

What is given alongside trimethoprim in the treatment of UTI/chest infections?

Answer 8

sulphamethoxazole

Question 9

Which protein synthesis inhibitor targets gram negative bacteria?

a) clarithromycin
b) teicoplanin
c) gentamicin

Answer 9

c)gentamicin

Question 10

Which group of antibiotics target topoisomerase in inhibiting DNA synthesis?

a) fluroquinolones
b) cyclic lipopeptides
c) tertracylines

Answer 10

a)fluroquinolones

Question 11

Which antibiotic can be used to replace penicillin in gram positive infection?

a) marcolides (erythromycin and clarithromycin)
b) oxazolidinones
c) ciprofloxacin

Answer 11

a)macrolides

Question 12

What type of bacteria is levofloxacin used to treat?

a) gram negative
b) gram positive
c) curved bacilli

Answer 12

b)gram positive

Question 13

Which protein synthesis inhibitors are effective against MRSA?

Answer 13

linezolid and daptomycin

Question 14

Which polyene is used for serious fungal infection?

a) amphotericin B
b) nystatin
c) terbinafine

Answer 14

a)amphotericin B

Question 15

What do Azoles target?

a) ergosterol synthesis
b) glucan polysaccharide synthesis
c) protein synthesis

Answer 15

a)ergosterol synthesis

Question 16

How is nystatin administered?

a) topical
b) oral
c) IV

Answer 16

a)topical

Question 17

What is fluconazole an example of?

a) azole
b) allylamines
c) echinocandins

Answer 17

a)azole

Question 18

What anti fungal is used for candida and aspergillum species?

a) allylamines
b) polyenes
c) echinocandins

Answer 18

c)echinocandins

Question 19

What is terbinafine?

a) polyenes
b) allylamine
c) azole

Answer 19

b)allylamine

Question 20

Which anti fungal binds erogesterol and increases membrane permeability?

a) azoles
b) echinocandins
c) polyenes

Answer 20

c)polyenes

Question 21

What are caspofungin, mycafungin and anidulafungin?

a) polyenes
b) allylamines
c) echinocandins

Question 22

What does aciclovir target?

a) HSV and VZV
b) HSV alone
c) VZV alone

Answer 22

a)herpes simplex and varicella zoster viruses

Question 23

When should zanamivir be given in relation to onset of symptoms?

a) within 24 hours
b) within 48 hours
c) within 12 hours

Answer 23

b)within 48 hours

Question 24

What is used in combination to treat HIV?

a) nevirapine and saquinavir
b) zanamivir and oseltamivir
c) famiclovir and valaciclovir