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Pharms > Antimicrobial names - Block 18a > Flashcards

Antimicrobial names - Block 18a Flashcards

(61 cards)

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1
Q

Benzylpenicillin

A

a. k.a pen G
- natural penicillin
- G+ cocci, G- cocci, G- bacilli, anaerobes, spirochetes

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2
Q

Amoxicillin

A
  • broad spectrum penicillin

- spectrum same as natural penicillins, but more G+ and G- bacilli

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3
Q

Ticarcillin

A

Extended (anti-pseudomonal) penicillin

-same spectrum as natural, but more G- bacilli and pseudomonas

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4
Q

Cefadroxil

A

1st Gen cephalosporin

-spectrum: G+ cocci, G- bacilli

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5
Q

Sparfloxacin

A

3rd Gen Fluoroquinolone

  • systemic aerobic G-‘s causing UTI’s
  • G+ resp infections
  • atypical MO
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6
Q

Oxacillin

A
  • B-lactamase resistant penicillin

- strep and staph

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7
Q

Cefamandole

A

2nd Gen cephalosporin

-G+ cocci, G- cocci, G- bacilli

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8
Q

Dicloxacillin

A
  • B-lactamase resistant penicillin

- strep and staph spectrum

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9
Q

Cephalothin

A

1st Gen cephalosporin

-spectrum: G+ cocci, G- bacilli

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10
Q

Cefoxitin

A

2nd Gen cephalosporin

  • G+ cocci, G- cocci, G- bacilli
  • B-lactamase resistant
  • active against anaerobes
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11
Q

Cefepime

A

4th Gen cephalosporin

-wide spectrum G+ and G-

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12
Q

Ampicillin

A
  • broad spectrum penicillin

- spectrum same as natural penicillins, but more G+ and G- bacilli

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13
Q

Cefdinir

A

3rd Gen cephalosporin

-Spectrum: G- cocci, G- bacilli (including pseudomonas)

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14
Q

Flucloxacillin

A
  • B-lactamase resistant penicillin

- strep and staph spectrum

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15
Q

Imipenem

A

Carbapenem

  • used with Cilastatin
  • G+ cocci, G- cocci, G- bacilli, Anaerobes, Actinomyces and Nocardia
  • broadest B-lactam coverage
  • concentration dependent with PAE
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16
Q

Cefoperazone

A

3rd Gen cephalosporin

-Spectrum: G- cocci, G- bacilli (including pseudomonas)

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17
Q

Meropenem

A

Carbapenem

  • broadest B-lactam coverage - G+, G-, anaerobes
  • concentration-dependent with PAE
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18
Q

Ertapenem

A

Carbapenem

  • broadest B-lactam coverage - G+, G-, anaerobes
  • concentration-dependent with PAE
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19
Q

Erythromycin

A

Macrolide

  • 2h half life
  • same spectrum as Pen G
  • inhibits CYP450
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20
Q

Ciprofloxacin

A

2nd Gen Fluoroquinolone

-Systemic aerobic G-‘s causing UTI’s

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21
Q

Piperacillin

A

Extended (anti-pseudomonal) penicillin

-same spectrum as natural, but more G- bacilli and pseudomonas

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22
Q

Clarithromycin

A

Macrolide

  • 3.5h half life
  • same spectrum as erythromycin (or Pen G), + more intracellular activity as well as against H. influenzae
  • inhibits CYP450
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23
Q

Azithromycin

A

Macrolide

  • half life >40h
  • less active against staph and strep, more against resp. infections
  • agent of choice for Chlamidia trachomatis
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24
Q

Telithromycin

A

Macrolide

  • 10h half life
  • inhibits CYP450
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25
Gatifloxacin
3rd Gen Fluoroquinolone - systemic aerobic G-'s causing UTI's - G+ resp infections - atypical MO
26
Tetracycline
broad spectrum G+, G-, and non-bacterial MO
27
Cefaclor
2nd Gen cephalosporin | -G+ cocci, G- cocci, G- bacilli
28
Norfloxacin
2nd Gen Fluoroquinolone | -Systemic aerobic G-'s causing UTI's
29
Doxycycline
broad spectrum G+, G-, and non-bacterial MO
30
Methicillin
- B-lactamase resistant penicillin | - strep and staph spectrum
31
Minocycline
- a tetracycline | - broad spectrum G+, G-, and non-bacterial MO
32
Cefprozil
2nd Gen cephalosporin | -G+ cocci, G- cocci, G- bacilli
33
Co-trimoxazole
Sulphamethoxazole-trimethoprim - sequential blockade - folate synthesis - UTI, resp. infections and PCP
34
Cefixime
3rd Gen cephalosporin | -Spectrum: G- cocci, G- bacilli (including pseudomonas)
35
Demeclocycline
- a tetracycline | - broad spectrum G+, G-, and non-bacterial MO
36
Chloramphenicol
-broad spectrum - G+, G- and anaerobes
37
Clindamycin
Primarily anaerobes, also non-enterococcal G+ cocci
38
Moxifloxacin
3rd Gen Fluoroquinolone - systemic aerobic G-'s causing UTI's - G+ resp infections - atypical MO
39
Amikacin
Aminoglycoside | -only Anaerobes!! - G- bacilli (including pseudomonas) and G+ cocci
40
Trovafloxacin
4th Gen Fluoroquinolone - Improved G+ coverage, maintained G- activity - Anaerobic cover
41
Gentamicin
Aminoglycoside | -only Anaerobes!! - G- bacilli (including pseudomonas) and G+ cocci
42
Vancomycin
- tricyclic glycoprotein - for multi-resistant organisms | - ONLY G+'s - cocci, bacilli, anaerobes, actinomyces
43
Tobramicin
Aminoglycoside | -only Anaerobes!! - G- bacilli (including pseudomonas) and G+ cocci
44
Cefotetan
2nd Gen cephalosporin - G+ cocci, G- cocci, G- bacilli - active against anaerobes
45
Rifampicin
Many G+ and G- - bactericidal for mycobacteria - meningococcal and H. influenza prophylaxis - anti-leprosy
46
Streptomycin
Aminoglycoside | -only Anaerobes!! - G- bacilli (including pseudomonas) and G+ cocci
47
Ofloxacin
2nd Gen Fluoroquinolone | -Systemic aerobic G-'s causing UTI's
48
Cloxacillin
- B-lactamase resistant penicillin | - strep and staph spectrum
49
Levofloxacin
3rd Gen Fluoroquinolone - systemic aerobic G-'s causing UTI's - G+ resp infections - atypical MO
50
Cefuroxime
2nd Gen cephalosporin - G+ cocci, G- cocci, G- bacilli - B-lactamase resistant
51
Cefotaxime
3rd Gen cephalosporin | -Spectrum: G- cocci, G- bacilli (including pseudomonas)
52
Cephalexin
1st Gen cephalosporin | -spectrum: G+ cocci, G- bacilli
53
Ceftazidime
3rd Gen cephalosporin | -Spectrum: G- cocci, G- bacilli (including pseudomonas)
54
Indanyl carbenicillin
Extended (anti-pseudomonal) penicillin | -same spectrum as natural, but more G- bacilli and pseudomonas
55
Nalidixic acid
1st Gen Fluoroquinolone - gives rise to all fluoroquinolones - narrow spectrum - confined to UTI's
56
Phenoxymethylpenicillin
a. k.a. pen V - natural penicillin - G+ cocci, G- cocci, G- bacilli, anaerobes, spirochetes
57
Ceftriaxone
3rd Gen cephalosporin | -Spectrum: G- cocci, G- bacilli (including pseudomonas)
59
Cefazolin
1st Gen cephalosporin | -spectrum: G+ cocci, G- bacilli
60
Ceftibuten
3rd Gen cephalosporin | -Spectrum: G- cocci, G- bacilli (including pseudomonas)
61
Ceftizoxime
3rd Gen cephalosporin | -Spectrum: G- cocci, G- bacilli (including pseudomonas)
62
Nafcillin
- B-lactamase resistant penicillin | - strep and staph spectrum

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