Antimicrobials Flashcards Preview

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Flashcards in Antimicrobials Deck (34):
1

Penicillin

Beta Lactam - used for Staphylococcus and Streptococcus
Inhibits cell wall synthesis (inhibit formation of peptidoglycan cross-links)

2

Cephalosporin

Beta Lactam
Inhibits cell wall synthesis

3

Monobactam

Beta Lactam
Inhibits cell wall synthesis
Only effective against aerobic Gram Negative

4

Carbapenem

Beta Lactam
Inhibits cell wall synthesis

5

Vancomycin

Glycopeptide
Inhibits cell wall synthesis
Used in MRSA
Only gram positive
2nd line treatment for C. difficile

6

Teicoplanin

Glycopeptide
Inhibits cell wall synthesis
Only gram positive

7

Streptomycin

Aminoglycoside
Inhibits protein synthesis
Inhibits 30S

8

Gentamicin

Aminoglycoside
Inhibits protein synthesis
Inhibits 30S

9

Tetracycline

Inhibits protein synthesis
Inhibits 30S

10

Clarithromycin

Macrolides
Inhibits protein synthesis
Inhibits 50S

11

Erythromycin

Macrolides
Inhibits protein synthesis
Inhibits 50S

12

Clindamycin

Lincosamides
Inhibits protein synthesis
Inhibits 50S

13

Lincomycin

Lincosamides
Inhibits protein synthesis
Inhibits 50S

14

Oxazolidones

Inhibits protein synthesis

15

Chloramphenicol

Inhibits protein synthesis

16

Fusidic Acid

Inhibits protein synthesis

17

Mupirocin

Inhibits protein synthesis

18

Quinolone

Inhibits nucleic acid synthesis

19

Sulphonamides

Inhibits nucleic acid synthesis

20

Rifamycins

Inhibits nucleic acid synthesis

21

Metronidazole

Inhibits nucleic acid synthesis
Used to treat anaerobes, C. difficile and protozoa

22

Nitrofurantoin

Inhibits nucleic acid synthesis
Used to treat UTIs - not in pregnancy

23

Trimethoprim

Inhibits nucleic acid synthesis
Used to treat UTIs - not in pregnancy

24

Polyenes

Bind to ergosterol in fungal cell membrane

25

Allylamines

Inhibit squalene epoxidase
Stops synthesis of ergosterol in fungal cell membrane

26

Azoles

Inhibits cytochrome P450
Stops synthesis of ergosterol in fungal cell membrane

27

Echinocandins

Inhibits synthesis of beta 1,3 glycan

28

Flucytosine

Inhibits protein and DNA synthesis

29

Griseofulvin

Binds to tubulin and inhibits mitosis

30

Amorolfine

Inhibits D14 reductase
Depletes ergosterol

31

Acylovir

Antiviral - inhibits DNA polymerases
Treats HSV, VZV, EBV, Cytomegalovirus

32

NRTIs

Nucleoside Reverse Transcriptase Inhibitors
Treatment for HIV and Hep B

33

Albendazole

Binds to tubulin
Treatment for cestodes and nematodes

34

Praziquantel

Treatment for trematodes