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Extra Revision > Antimicrobials > Flashcards

Antimicrobials Flashcards

(34 cards)

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1
Q

Penicillin

A

Beta Lactam - used for Staphylococcus and Streptococcus

Inhibits cell wall synthesis (inhibit formation of peptidoglycan cross-links)

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2
Q

Cephalosporin

A

Beta Lactam

Inhibits cell wall synthesis

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3
Q

Monobactam

A

Beta Lactam
Inhibits cell wall synthesis
Only effective against aerobic Gram Negative

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4
Q

Carbapenem

A

Beta Lactam

Inhibits cell wall synthesis

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5
Q

Vancomycin

A 
Glycopeptide 
Inhibits cell wall synthesis 
Used in MRSA
Only gram positive 
2nd line treatment for C. difficile
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6
Q

Teicoplanin

A

Glycopeptide
Inhibits cell wall synthesis
Only gram positive

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7
Q

Streptomycin

A

Aminoglycoside
Inhibits protein synthesis
Inhibits 30S

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8
Q

Gentamicin

A

Aminoglycoside
Inhibits protein synthesis
Inhibits 30S

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9
Q

Tetracycline

A

Inhibits protein synthesis

Inhibits 30S

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10
Q

Clarithromycin

A

Macrolides
Inhibits protein synthesis
Inhibits 50S

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11
Q

Erythromycin

A

Macrolides
Inhibits protein synthesis
Inhibits 50S

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12
Q

Clindamycin

A

Lincosamides
Inhibits protein synthesis
Inhibits 50S

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13
Q

Lincomycin

A

Lincosamides
Inhibits protein synthesis
Inhibits 50S

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14
Q

Oxazolidones

A

Inhibits protein synthesis

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15
Q

Chloramphenicol

A

Inhibits protein synthesis

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16
Q

Fusidic Acid

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A

Inhibits protein synthesis

17
Q

Mupirocin

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A

Inhibits protein synthesis

18
Q

Quinolone

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A

Inhibits nucleic acid synthesis

19
Q

Sulphonamides

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A

Inhibits nucleic acid synthesis

20
Q

Rifamycins

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A

Inhibits nucleic acid synthesis

21
Q

Metronidazole

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A

Inhibits nucleic acid synthesis

Used to treat anaerobes, C. difficile and protozoa

22
Q

Nitrofurantoin

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A

Inhibits nucleic acid synthesis

Used to treat UTIs - not in pregnancy

23
Q

Trimethoprim

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A

Inhibits nucleic acid synthesis

Used to treat UTIs - not in pregnancy

24
Q

Polyenes

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A

Bind to ergosterol in fungal cell membrane

25
Allylamines
Inhibit squalene epoxidase | Stops synthesis of ergosterol in fungal cell membrane
26
Azoles
Inhibits cytochrome P450 | Stops synthesis of ergosterol in fungal cell membrane
27
Echinocandins
Inhibits synthesis of beta 1,3 glycan
28
Flucytosine
Inhibits protein and DNA synthesis
29
Griseofulvin
Binds to tubulin and inhibits mitosis
30
Amorolfine
Inhibits D14 reductase | Depletes ergosterol
31
Acylovir
Antiviral - inhibits DNA polymerases | Treats HSV, VZV, EBV, Cytomegalovirus
32
NRTIs
Nucleoside Reverse Transcriptase Inhibitors | Treatment for HIV and Hep B
33
Albendazole
Binds to tubulin | Treatment for cestodes and nematodes
34
Praziquantel
Treatment for trematodes

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