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IHO Wk 5 > Antioxidants--Goueli > Flashcards

Antioxidants--Goueli Flashcards

1
Q

Vitamin C deficiency

A

impaired wound healing

bleeding ecchymoses

swollen gums

anemia

enlargement and keratosis of follicles

lethergy

depression

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2
Q

Mechanism of reperfusion injury

A

reduced electron carriers overwhelmed when oxygen becomes available from reperfusion

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3
Q

Chronic granulometous disease mechanism

A

NADPH oxidase subunit mutation

–> enzyme that doesn’t function properly

*more suceptible to catalase + organisms

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4
Q

Catalase mechanism

A

reduces H2O2 to water

*mostly in peroxisomes

*prevents Fenton rxn and Haber-Weiss reaction

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5
Q

Superoxide dysmutase mechanism

A

O2- + 2 H+ => H2O2

then later…

H2O2 => 2 H2O + O2

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IHO Wk 5 (8 decks)

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