antiseizure

Question 1

what drug is a hydantoin

Answer 1

phenytonin
anticonvulsant

Question 2

what is the MOA of phenytoin

Answer 2

decreases excitability in the brain preventing seizure activity

Question 3

what kind of protein bound is phenytoin

Answer 3

highly protein bound

Question 4

what is the therapeutic level for phenytoin

Answer 4

10-20

Question 5

what is the half life of phenytoin

Answer 5

7-60hr

Question 6

what is hydantoin used for

Answer 6

treat tonic-colic and partial seiz.
status eplipeticus

Question 7

what are some side effects of phenytoin

Answer 7

HA, dizzy, drowsy, depression
gingival hyperplasia
hyperglycemia
urine discoloration-pink-red-brow

Question 8

what are some adverse effects of phenytoin

Answer 8

thrombocytopenia
SI
steven johnson synd
hypotension

Question 9

what is a contraindication for phenytoin

Answer 9

pregnancy

Question 10

what does phenytoin interact with

Answer 10

decrease effect
-anticoags
-oral contraceptives

decrease folic acid and Vit.K
decrease absorption of Calcium and vit D

Question 11

what should you teach a pt who is taking phenytoin

Answer 11

avoid asprin
increase intake of folic acid, Vit D and K and calcium

Question 12

what lab values would you check when giving phenytoin

Answer 12

BUN
creat
liver enzyme
UO

Question 13

what herbs alter phenytoin

Answer 13

evening primrose-lower seiz threshold
ginkgo- decrease effectiveness

Question 14

What are some nursing intervetions when giving phenytoin

Answer 14

monitor drug level
get a CBC to detect for blood dyscrais
make sure pt is getting enoiugh food- can cause anorexia
use another form of contraceptive

Question 15

what should you teach a pt taking phenytoin

Answer 15

dont drive
talk to doc if wanting to get pregnant
avoid alcohol and other CNS depressatns
do not stop abruptly
if pt diabetic watch glucose closley
dont take OTC meds

Question 16

how should pt take phenytoin

Answer 16

at same time everyday with food or milk

Question 17

what can we teach pt abt side effects of phenytoin

Answer 17

urine may be pink or red brown which is fine
keep good oral hygiene
report ST, bruising and nose bleeds-blood dyscrasia

Question 18

what can happen if you abruplty stop phenyotin

Answer 18

seizure rebound and status epliepticus

Question 19

how is phenytoin given

Answer 19

IV

Question 20

what is the MOA of levetiracetam

Answer 20

interfers with calcium dependent release of neurotransmitters

Question 21

what is levetiracetam

Answer 21

misc. antizeizure

Question 22

what is levetiracetam used for

Answer 22

partial and myoclonic, tonic-clonic
prevent substance withdrawl seiz.

Question 23

what are some side effects of levetiracetam

Answer 23

dizzy, drowst, HA
N&V
anorexia

Question 24

what are some adverse reactions to levetiracetam

Answer 24

renal toxicity
aggitaton, aggression, depression
confusion, SI
ataxia
SJS
DRESS

Question 25

what is the half life of levetiracetam

Answer 25

6-8hr

Question 26

how is levetiracetam given

Answer 26

PO

Question 27

what does levetiracetam interact with

Answer 27

alcohol, cannabis decrease effectiveness with other antiseiz. drugs

Question 28

what are the containdicatons/cautions when giving levetiracetam

Answer 28

hypersensitivity reduces dose bc of renal impairment SI

Question 29

Nursing interventions for levetiracetam

Answer 29

monitor mental status-1st 4-6wk water for hypersenstivity reactions suicide assessment avoid activites that need alertness until effect is known

Question 30

what type of drug is gabapentin

Answer 30

antiseizure

Question 31

what is the MOA of gabapentin

Answer 31

unknown has analgesic activity minimal protein binding

Question 32

what is gabapentine use for

Answer 32

seizures neuropathic pain restless leg syndrome

Question 33

how is gabapentin given

Answer 33

PO

Question 34

what is the half life of gabapentin

Answer 34

5-7hr

Question 35

what are some side effects of gabapentin

Answer 35

dizzy, drowsy, HTN anorexia gingivitis weight gain

Question 36

what are some adverse reactions to gabapentin

Answer 36

neruobehaviroal SJS angioedema ataxia rhabdomyolysis-elevated creat vision disturbance