antiviral drugs Flashcards
what is acyclovir and Zostavax used for
shingles
what is the MOA of non-hiv antiviral drugs
blocks the viral replication, it supresses symptoms but doesn’t cure
what is the drug example for non-hiv antiviral drugs: dose limiting toxicities
amantadine, acyclovir and ganciclovir
what is amantadine effective against
influenza a
what is acyclovir effective against
HSV 1, HSV 2 and VZV
what is ganciclovir effective against
infections caused by CMV
what is the drug example for non-hiv antiviral drugs: neuraminidase inhibitors
oseltamivir
what drug treats hep c
ribavarin
what type of drug is ribavirin
antiviral non-hiv
what is the inhalation form of ribavirin
virazole
what are the two subclasses of reverse transcriptase inhibitors
nucleoside reverse trascriptase inhibitors and non-nucleoside reverse transcriptase inhibitors
what is the MOA of reverse transcriptase inhibitors
block activity of the enzyme reverse transcriptase, preventing production of new viral DNA
what is the mechanism of action of protease inhibitors
inhibit the protease retroviral enzyme, preventing viral replication
what is the mechanism of action of fusion inhibitors
inhibit viral fusion, preventing viral replication
what class is indinavir
protease inhibitor classs
