Antivirals

Question 1

Acyclovir

Indications?

Dosage Forms?

Answer 1

Zovirax
* Buccal form should be avoided in patients with a milk protein allergy
* BUN and SCr will be monitored (with prolonged therapy)
* Patients should stop taking med at least 24 hours before, and 14 days after, varicella vaccine
* Should be avoided in patients who also take kidney toxic drugs (lithium, mathotrexate, etc.)

Viral infections

Injectable, oral solid, liquid, topical

Question 2

Docosanol

Indications?

Dosage Forms?

Answer 2

Abreva
* Should not be used in kids under 12

Herpes (cold sores)

Topical

Question 3

Famciclovir

Indications?

Dosage Forms?

Answer 3

Famvir
* BUN and SCr will be monitored (with prolonged therapy)
* Patients should stop taking med at least 24 hours before, and 14 days after, varicella vaccine

Viral infections

Oral solid

Question 4

Foscarnet

Indications?

Dosage Forms?

Answer 4

Foscavir
* BUN, CBC, ECG, and SCr will be monitored (with prolonged therapy)
* May cause electrolyte imbalances
* Must be infused slowly

Viral infections

Injectable

Question 5

Ganciclovir

Indications?

Dosage Forms?

Answer 5

Cytovene
* BUN, CBC, LFTs, and SCr will be monitored (with prolonged therapy)
* May cause bone marrow suppression
* Must be infused slowly (with injectable)
* Patients should stop taking at least 7 days before starting cidofovir

Viral infections

Injectable, ophthalmic

Question 6

Imiquimod

Indications?

Dosage Forms?

Answer 6

Aldara
* Can weaken barrier contraceptive devices (condoms, etc) when applied in the pubic area

Genital herpes

Topical

Question 7

Oseltamivir

Indications?

Dosage Forms?

Answer 7

Tamiflu
* Must be started within 48 hours of flu symptoms
* Patients should stop taking med at least 2 weeks before, or 48 hours after, intranasal LAIV

Influenza

Oral powder (suspension), oral solid

Question 8

Remdesivir

Indications?

Dosage Forms?

Answer 8

Veklury
* Should be avoided in patients who take chloroquine or hydrochloroquine

COVID-19

Injectable

Question 9

Valacyclovir

Indications?

Dosage Forms?

Answer 9

Valtrex
* BUN and SCr will be monitored (with prolonged therapy)
* Patient should stop taking med at least 24 hours before, and 14 days after, varicella vaccine
* Should be avoided in patients who take kidney toxic drugs (lithium, methotrexate, etc.)

Viral infections

Oral solid

Question 10

Valganciclovir

Indications?

Dosage Forms?

Answer 10

Valcyte
* BUN, CBC, and SCr will be monitored (with prolonged therapy)
* May cause bone marrow suppression
* NIOSH med
* Should be avoided in patients who take kidney toxic drugs (lithium, methotrexate, etc.)

Viral infections

Oral solid, oral powder (suspension)

Question 11

Zanamivir

Indications?

Dosage Forms?

Answer 11

Relenza
* Must be started within 48 hours of flu symptoms
* Patients should stop taking med at least 2 weeks before, or 48 hours after, intranasal LAIV

Influenza

Inhalation powder

Question 12

Cabotegravir

Indications?

Dosage Forms?

Answer 12

Apretude
* High-alert med
* Must be injected by a healthcare provider
* Patient must be HIV negative before starting therapy

HIV PrEP

Injectable, oral solid

Question 13

Emtricitabine/tenofovir alafenamide

Indications?

Dosage Forms?

Answer 13

Descovy
* BUN and SCr will be monitored
* High-alert med
* Patient must be HIV negative before starting therapy
* Should use with caution if pregnant or breastfeeding

HIV PrEP

Oral solid

Question 14

Emtricitabine/tenofovir disoproxil

Indications?

Dosage Forms?

Answer 14

Truvada
* BUN and SCr will be monitored
* High-alert med
* Patient must be HIV negative before starting therapy

HIV PrEP, HIV PEP

Oral solid