Antivirals Flashcards

(17 cards)

1
Q

DNA polymerase drugs : valacicolvir
Is used to treat CMV

A

False : used to treat shingle (VCV)

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2
Q

Valaciclovir is useful in immunocompromised patients

A

True

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3
Q

Match DNA polymerase drugs to use
1. Aciclovir - CMV
2. Valaciclovir - shingles
3. Ganiciclovir - orolabial and genitalia herpes
4. Penciclovir - CMV retinas

A
  1. Aciclovir - false - HSV1 + 2 and VCV
  2. Valaciclovir - true
  3. Ganiciclovir - false - CMV retinas
  4. Penciclovir - false- orolabial and genital herpes
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4
Q

Foscarnet is a non nucleotide DNA polymerase drug

A

True

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5
Q

Foscarnet is used to RX CMV and has A/E of Nephrotoxicity

A

True

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6
Q

Foscarnet used to treat hepatitis B

A

False - used to treat herpes , CMV

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7
Q

Interferon alpha is ant anti hepatitis drug

A

True

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8
Q

Interferon alpha true or false
1. Natural occurring glycoproteins
2. Does not bind to IFN receptor and doesnt inhibits protein synthesis
3. Used to treat chronic HBV and HCV
4. Has immunodulatory effects

A
  1. True
  2. False - does bind and inhibit protein synthesis
  3. True
  4. True
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9
Q

Anti hepatitis : ribavarin
1. Broken down by adenosine kinase
2. R monophosphate occurs in 90-95% of cell
3. R monophosphate results in inhibition of viral protein synthesis
4. R triphosphate inhibits RNA synthesis which stops guanyltransferase enzyme

A
  1. True
  2. False. 5-10
  3. True
  4. True
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10
Q

Tenovir is an antiviral also used to treat HIV . Used as an ARV

A

True

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11
Q

Tenovir is an antiviral also used to treat HIV . Used as an ARV

A

True

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12
Q

Tenovir is hepatotoxic

A

False. Nephrotoxic

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13
Q

Tenovir used to treat hepatitis A

A

False - hep B

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14
Q

Entecavir is used for influenza

A

False hepatitis , HBV and liver infections cause by hep B

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15
Q

Amatadine and rimatadine are neuroamides

A

False- they are M2 protein inhibitors
Oseltamivir and zanamivir are neuroamides

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16
Q

DNA viruses are protected by replications

A

False- RNA viruses ‘
DNA viruses are in capsid shells

17
Q

DNA viruses are protected by replications

A

False- RNA viruses ‘
DNA viruses are in capsid shells