Antivirals Flashcards
(17 cards)
DNA polymerase drugs : valacicolvir
Is used to treat CMV
False : used to treat shingle (VCV)
Valaciclovir is useful in immunocompromised patients
True
Match DNA polymerase drugs to use
1. Aciclovir - CMV
2. Valaciclovir - shingles
3. Ganiciclovir - orolabial and genitalia herpes
4. Penciclovir - CMV retinas
- Aciclovir - false - HSV1 + 2 and VCV
- Valaciclovir - true
- Ganiciclovir - false - CMV retinas
- Penciclovir - false- orolabial and genital herpes
Foscarnet is a non nucleotide DNA polymerase drug
True
Foscarnet is used to RX CMV and has A/E of Nephrotoxicity
True
Foscarnet used to treat hepatitis B
False - used to treat herpes , CMV
Interferon alpha is ant anti hepatitis drug
True
Interferon alpha true or false
1. Natural occurring glycoproteins
2. Does not bind to IFN receptor and doesnt inhibits protein synthesis
3. Used to treat chronic HBV and HCV
4. Has immunodulatory effects
- True
- False - does bind and inhibit protein synthesis
- True
- True
Anti hepatitis : ribavarin
1. Broken down by adenosine kinase
2. R monophosphate occurs in 90-95% of cell
3. R monophosphate results in inhibition of viral protein synthesis
4. R triphosphate inhibits RNA synthesis which stops guanyltransferase enzyme
- True
- False. 5-10
- True
- True
Tenovir is an antiviral also used to treat HIV . Used as an ARV
True
Tenovir is an antiviral also used to treat HIV . Used as an ARV
True
Tenovir is hepatotoxic
False. Nephrotoxic
Tenovir used to treat hepatitis A
False - hep B
Entecavir is used for influenza
False hepatitis , HBV and liver infections cause by hep B
Amatadine and rimatadine are neuroamides
False- they are M2 protein inhibitors
Oseltamivir and zanamivir are neuroamides
DNA viruses are protected by replications
False- RNA viruses ‘
DNA viruses are in capsid shells
DNA viruses are protected by replications
False- RNA viruses ‘
DNA viruses are in capsid shells