Antivirals Flashcards Preview

Pharmacology > Antivirals > Flashcards

Flashcards in Antivirals Deck (19)
Loading flashcards...
1
Q

Drugs used for herpes

A

Acyclovir, ganciclovir, foscarnet

2
Q

Drugs for influenza

A

Amantadine, zanamivir

3
Q

Drugs for HBV and HCV

A

Inf-a, lamivudine, ribavirin

4
Q

Activated by thymidine kinase to formals that inhiit viral DNA polymerase

A

Acycolvir

5
Q

Inhibits viral DNA polymerase , causing chain termination

A

Ganciclovor

6
Q

Inhibits RNA polymerase, DNA polymerase and HIV reverse transcriptase. Binds to pyrophosphate binding site.

A

Foscarnet

7
Q

DOC for CMV retinits(?)

A

Cifodovir

8
Q

Antiviral that can cause hypocalcemia

A

Foscarnet

9
Q

Drugs for HIV

A

Indinavir, enduvirtide, maraviroc, zidovudine, delavirdine (nucleoside reverse transcriptase inhibitor, nnrti, protease inhibitor, fusion inhibitor, ccr5 receptor antagonist)

10
Q

Inhibits HIV transcriptase after phosphorylation by cellular enzymes

A

Zidovudine

11
Q

Inhibit reverse transcriptase. No phosphorylation required.

A

Delavirdine

12
Q

Inhibits viral protein processing

A

Indinavir

13
Q

Binds to gp41 subunit of viral envelope glycoprotein, preventing fusion of viral and cellular membranes

A

Enfuvirtide

14
Q

Blocks viral attachment via transmembrane chemokine receptor CCR5

A

Maraviroc

15
Q

Inhibit early step replication and prevent UNCOATING by binding yo M2 proton channels

A

Amantadine

16
Q

Inhibits neuraminidase. Decreases release of progeny virus.

A

Oseltamivir

17
Q

Degrades viral RNA via activation of host cell RNAase(ribonuclease)

A

Interferon a

18
Q

Inhibits HBV DNA polymerase

A

Lamivudine

19
Q

Inhibits guanosine triphosphate formation. Prevents capping of viral mRNA. Blocks RNA dependent RNA polymerase

A

Ribavirin