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Antimicrobial chemotherapy > Antivirals > Flashcards

Antivirals Flashcards

1
Q

Aciclovir is what type of drug?

A

Anti Herpes virus

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2
Q

Famiciclovir and Valaciclovir are what?

A

Similar drugs to Aciclovir, oral admin

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3
Q

What is Aciclovir used for?

A

Treatment of HSV and VZV

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4
Q

Describe Foscarnet and its use

A

Non-nucleoside analogue herpes virus drug.

Used to treat analogue resistant HSV, VZV and CMV

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5
Q

Ganciclovir is used for what?

A

Treatment of serious CMV infection, usually in immunocomp. patients.

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6
Q

What kind of drug is Ganciclovir?

A

Nucleoside analogue, used for treatment of serious CMV

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7
Q

Topical Aciclovir is used for treatment of what?

A

Coldsore type HSV infection

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8
Q

Name the three main anti-HIV drugs

A

AZT (zivovudine), Saquinavir, nevirapine

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9
Q

What is the mech. of action of AZT

A

inhibits viral reverse transcriptase

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10
Q

All antivirals are…

A

virustatic

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11
Q

Lamivudine can be used to treat?

A

Hep B and has efficacy against HIV

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12
Q

What is the main drug for Hepatitis B/C treatment

A

Pegylated Interferon a.

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13
Q

How is Interferon PEG administered and what are it’s effects?

A

Subcutaneous injection. Treatment of Hep B/C. serious side effects.

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14
Q

What type of drug is Lamivudine?

A

Nucleoside analogue for Hep B/C treatment and HIV

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15
Q

Oseltamivir and Zanamivir are used to treat…

A

Influenza A and B

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16
Q

What type of drug is Ribavarin and what is it’s use?

A

Nucleoside analogue, treatment of severe Respiratory Syncytial Virus

17
Q

What is the application of Cidofovir?

A

Treatment of CMV retinitis when other herpes virus drugs cannot be used

18
Q

What is Ganciclovir used to treat and what are its side effects?

A

Sever CMV, usually in immunocomp. patients. Can cause bone marrow deficiency.

19
Q

Describe the use of ribivarin?

A

Treatment of severe Respiratory Syncytial Virus infections. Nucleoside analogue, admin by mist spray into lungs.

20
Q

Anti herpes virus are effective when…

A

Started early in infection.

21
Q

Anti-Herpes virus drugs generally have…

A

renal and hepatotoxicity

Antimicrobial chemotherapy (3 decks)

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