Anxiety

Question 1

When does anxiety become a disorder?

Answer 1

overwhelming and affecting function and quality of life

Question 2

2 main qualities of anxiety?

Answer 2

Fear and Worry

Question 3

Psychological sx of anxiety?

Answer 3

fear
worry
apprehension
difficulty concentrating

Question 4

Physical sx of anxiety?

Answer 4

Increased HR
Tremor
Sweating
GI upset

Question 5

Amygdala centered sx?

Answer 5

Fear, panic, phobia

Question 6

CSTC centered sx?

Answer 6

Worry, anxious misery, apprehensive, expectation, obsessions

Question 7

Amygdala Characteristics?

Answer 7

Almond shaped near hippocampus
Interprets sensory and cognitive info and determines if there will be a fear response

Question 8

CSTC regulated by?

Answer 8

COMT

Question 9

GABA anxiety role?

Answer 9

role in anxiolytics
inhibitory NT that decreases activities of neurons

Question 10

Voltage sensitive Ca channel subtypes?

Answer 10

N, P/Q

Question 11

What drugs bind to the alpha2delta ligands of the N and P/Q VSCCs?

Answer 11

Pregabalin
Gabapentin

Question 12

What does binding of the alpha2delta ligand of the N and P/Q VSCC do?

Answer 12

blocks the release of glutamate

Question 13

5-HT does?

Answer 13

NT that innervates the amygdala and CSTC

Question 14

What drug classes block the 5-HT reuptake by blocking the 5-HT transporter?

Answer 14

SSRI
SNRI

Question 15

Buspirone use? why?

Answer 15

only for GAD, 5-HT1A agonist

Question 16

SNRI short term vs long term?

Answer 16

SHort bad b/c can worsen sx but, long term once beta1 receptors downregulate the fear/worry seem to improve

Question 17

NE regulator of amygdala and which parts of the CSTC?

Answer 17

PFC/thalamus

Question 18

SSRI/SNRI 1st line for?

Answer 18

GAD, PD, SAD,PTSD, OCD

Question 19

Pregabalin/gabapentin 1st line for?

Answer 19

GAD, SAD

Question 20

Prazosin 1st line for?

Answer 20

trauma related nightmares in PTSD

Question 21

Propranolol, atenolol use?

Answer 21

for performance related SAD

Question 22

Medication considerations (chart)

Answer 22

Question 23

GAD more common in male or female?

Answer 23

Female 2:1 ratio

Question 24

Onset of GAD?

Answer 24

late adolescents or early adulthood

Question 25

Medical conditions potentially that can cause GAD?

Answer 25

CV Neurological Respiratory

Question 26

Meds that maybe cause GAD?

Answer 26

antidepressants Corticosteroids Stimulants Sympathomimetics