Anxiety And Eating Disorders Flashcards

(49 cards)

1
Q

Biological aetiology of anorexia nervosa

A

MZ twin concordance higher than DZ twins
Neuro / endocrine changes (disturbance of hypothalamic function, increased serotonin levels, brain atrophy)
Changes in brain normalise when weight is restored though regular balanced diet

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2
Q

Psychological aetiology of anorexia nervosa

A

Perfectionism
Low self esteem
Sexual development
History of abuse
Personality disorder

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3
Q

Social aetiology of anorexia nervosa

A

Parental overprotection
Family enmeshment

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4
Q

Biological aetiology of bulimia nervosa

A

Changes in serotonin levels
MZ and DZ twin concordance rates broadly similar

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5
Q

Psychological aetiology of bulimia nervosa

A

Low self esteem
History of abuse / self harm
Impulsive personality traits
Personality disorder
High value placed on food and eating behaviour
History of being overweight

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6
Q

Social aetiology of bulimia nervosa

A

Exposure to diet culture
Family culture of categorising food as good or bad

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7
Q

Hair and skin effects of anorexia

A

Can become dry and brittle
Hair can thin and drop out
Lanugo hair may grow over the skin on face and body aiming to aid warmth

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8
Q

Psychiatric effects of anorexia

A

Difficult to make decisions
Poor concentration
Obsessions - difficulty being spontaneous
Interests become centred around food
Irritated mood
Flattened affect

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9
Q

Heart effects of anorexia

A

BP drops
Pulse declines
Increased risk of arrhythmia
Risk of heart failure

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10
Q

Reproductive system effects of anorexia

A

Lack of sex drive
Lack of function
Amenorrhoea in females
Low testosterone in males
Function usually returns with weight restoration

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11
Q

CNS effects of bulimia nervosa

A

Poor concentration
Irritability
Seizures

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12
Q

Oral effects of bulimia nervosa

A

Tooth decay / erosion
Hoarse voice
Bleeding from the mouth or throat
Swollen parotid glands

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13
Q

Heart effects of bulimia nervosa

A

K+ is crucial to heart function
Hyopkalaemia can cause arrhythmias and can be fatal
This is caused by the use of diuretics, D&V and laxative use

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14
Q

Hand effects of bulimia nervosa

A

Russell sign - callosities, scarring and abrasion on the dorsal surface of index and long fingers as a result of self induced vomiting

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15
Q

Define generalised anxiety disorder

A

Anxiety to the point that it severely impairs a patients day to day functioning
Thoughts of being apprehensive / nervous as well as the awareness of a physical reaction to anxiety
Often leads to behavioural changes to try and avoid the threat

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16
Q

Organic causes of anxiety

A

Any condition causing dyspnoea or increased sympathetic outflow
Drug intoxication
Withdrawal symptoms
Medication side effects

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17
Q

Epidemiology of anxiety

A

3-4% prevalence
2:1 F:M
Commonly seen with co-morbid depression or phobic disorders

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18
Q

Biological aetiology of anxiety

A

Genetic links (overlaps with depression)
Amygdala hyperactivation
Evidence on neurotransmitter imbalances is conflicting

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19
Q

Psychological aetiology of anxiety

A

Negative cognitive biases
Personality factors (neuroticism)

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20
Q

Social aetiology of anxiety

A

Increased negative / traumatic childhood events

21
Q

Clinical features of anxiety

A

Not episodic
Not associated with any specific external threat
Characterised by excessive worry about normal events

22
Q

What is paroxysmal anxiety

A

Abrupt onset episodes
Termed panic disorder at its most severe

23
Q

Biological Symptoms of anxiety

A

Autonomic overactivity:
- heart racing
- sweating
- hyperventilation
- restlessness
- fidgeting
- tension headaches
- sleep disturbances

24
Q

Psychological symptoms of anxiety

A

Persistent worrisome thoughts
Apprehension about future
Poor concentration

25
Psychological management of anxiety
CBT is first line Identify and challenge cognitive biases such as catastrophic thinking, and recognise learnt behaviours based upon such biases Relaxation therapy can also be used
26
Biological management of anxiety
SSRIs - 1st line for moderate severe symptoms only - 2nd line is an alternate SSRI, or SNRI - drugs generally take longer to work and need to be titration to higher doses to be effective in anxiety disorders Benzodiazepines - potentiate GABA - effective in rapidly reducing anxiety symptoms - rapid tolerance and dependence syndrome so avoided where possible Non selective beta blockers - can be used prn to dampen symptoms of autonomic arousal
27
Social management of anxiety
Ensure social support structures are in place Reduce alcohol / illicit drug use
28
Prognosis of generalised anxiety disorder
Chronic, fluctuating course
29
Define phobia
An intense, irrational fear of an activity or situation
30
Epidemiology of phobias
Prevalence of all phobias is around 8%
31
Aetiology of phobias
Specific phobias can often be traced back to childhood exposures - genetic predisposition for some objects to evoke fear and behavioural conditioning can re-enforce this fear Agoraphobia and social phobias are poorly understood All involve some level of amygdala dysregulation
32
Clinical features of phobias
Intense symptoms of anxiety related to a discernible object / situation Can manifest as panic attacks at their most severe
33
Features of agoraphobia
Fear of public places (crowds, queues, public transport) Can become housebound Classically a fear of a lack of a clear exit More common in females
34
Features of social phobia
Fear of social situations in which they may be exposed to scrutiny eg fear of eating in public Can progress to almost all social situations - patients describe fear of going mad or vomiting in public More commonly seen in males (most comfortable when alone) Linked to alcohol abuse
35
Describe management of phobias
1st line is psychotherapy (CBT) - involved graded exposure (desensitisation) SSRIs can be useful for agoraphobia / social phobia Benzodiazepines are occasionally used for rarely occurring situations eg flying
36
Prognosis of phobias
Specific phobias held from childhood are unlikely to remit Social phobias are usually chronic but may have periods of remission
37
Describe the characteristics of the obsessions in OCD
- involuntary thoughts, images or impulses that are recurrent, intrusive and unpleasant - enter the mind against conscious resistance and are recognised as being the produce of their own mind - patients generally have insight into the fact that the thoughts are irrational
38
Describe the characteristics of the compulsions in OCD
Repetitive mental operations eg counting, praying or physical acts eg checking, hand washing - patient feels compelled to perform this act in response to their own obsessions or irrationally defined rules The acts are performed to reduce anxiety through the belief that they will stop a dreaded event from occurring Resisting a compulsion can lead to increased anxiety
39
Describe the aetiology and epidemiology of OCD
Epi: prevalence of 2%, equal M:F Aeti: genetic predisposition to develop symptoms Symptoms common in childhood Mean time from onset of symptoms to diagnosis is 9yrs
40
Which conditions frequently co-exist with OCD
Schizophrenia, Tourette’s or depression
41
Describe the pathophysiology of OCD
1. Damage to the cortico-striato-thalamo-cortical circuits following neurological injury eg stroke can invoke symptoms of OCD 2. Neurosurgical interruption of these circuits has also been shown to induce response in OCD patients resistant to all other treatments
42
What is the diagnostic criteria for OCD
Obsessions or compulsions present for at least 2 successive weeks Source of distress and / or interfere with the patients functioning They are acknowledged as coming from the patients own mind Obsessions are unpleasantly repetitive At least one thought / act is resisted unsuccessfully A compulsive act is not in itself pleasurable
43
Psychological management of OCD
CBT is 1st line, involving exposure response prevention Aims to break the cycle of behaviour by exposing the patient to their obsession but preventing the compulsive response
44
Biological management of OCD
SSRIs considered for moderate - severe symptoms
45
Social management of OCD
Optimise social support structures, screen for substance abuse
46
Prognosis of OCD
Mainly chronic fluctuating course, with around 15% showing a progressive decline in functioning
47
Aetiology / epidemiology of adjustment disorder
Most common in children and adolescents but can happen in any age Around 1% prevalence equal M:F More common in those with mental health history and low social support
48
Diagnostic criteria of adjustment disorder
- maladaptive reaction to psychosocial stressors, causing an impairment of function - must develop within 3 months of a stressful life event - symptoms do not generally last >6 months
49
What is the difference between acute stress disorder and PTSD
Acute stress disorder is an acute stress reaction that occurs in the 4 weeks after a traumatic event as opposed to PTSD which is diagnosed after 4 weeks