Anxiety and Trauma and Stressor Related Disorder

Question 1

Benzodiazepines Drugs

Answer 1

-pams and -lams
Diazepam, lorazepam, chlordiazepoxide, clorazepate, oxazepam, clonazepam

Question 2

Benzos purpose

Answer 2

Sedative hypnotic anxiolytic
inhibits GABA in the CNS eliciting relief from anxiety. Short term use because of potential dependence.

Question 3

Benzo Therapeutic Uses

Answer 3

General anxiety disorder, panic disorders, trauma, acute stress disorder, PTSD, seizures, insomnia, muscle spasm, alcohol withdrawal, induction of anesthesia, and amnesic for surgery..

Question 4

What is barbiturate and nonbarbiturate

Answer 4

Barbiturate have hypnotic or sedative; vice versa

Question 5

Which drug is nonbarbiturate/atypical anxiolytic?

Answer 5

Buspirone

Question 6

Complication of Benzo

Answer 6

CNS Depression (sedation and ataxia: overall poor muscle control)
Anterograde Amnesia
Toxicity
Paradoxical response
Withdrawal Effects

Question 7

Benzo acute toxicity protocol

Answer 7

S/S: respiratory depression, severe hypotension, or cardiac/respiratory arrest

Nursing Action:
Flumazenil (reversal agent) and resuscitation equipment ready.

Question 8

Benzo Withdrawal Effect S/S

Answer 8

Anxiety, insomnia, diaphoresis, tremors, lightheadedness, delirium, HTN, muscle twitching, and seizures

Question 9

Benzo Contraindication

Answer 9

Dependence, pregnancy (can transfer from milk), sleep apnea, respiratory depression, glaucoma, and liver disease

Question 10

Benzo interaction

Answer 10

CNS depression, grapefruit juice, high fat meals.

Question 11

Benzo administration

Answer 11

Administer with meals and at bedtime if possible

Question 12

Atypical anxiolytic/nonbarbiturate anxiolytic drugs

Answer 12

Buspirone

Question 13

Atypical Anxiolytic mechanism

Answer 13

Binds to serotonin and dopamine receptors

Question 14

What are the function of serotonin and dopamine?

Answer 14

Serotonin
Controls mood by influencing sleep, pain, sexual desire, and increase in serotonin may help with depression

Dopamine
Controls feeling of purpose, pleasure, satisfaction, and motivation.

Question 15

Buspirone complications

Answer 15

GI problems (take with food), constipation, and SI

Question 16

Buspirone contraindivations

Answer 16

Pregnancy, decrease liver or kidney function, concurrent use with MAOI (can use after stopping for 14 days of MAOIs use - HTN crisis can occur)

Question 17

SSRI Drugs

Answer 17

Paroxetine, sertraline, citalopram, escitalopram, fluoxetine, fluvoxamine