Anxiety, Panics, Phobias & OCD Flashcards

(36 cards)

1
Q

What are the physical symptoms of anxiety?

A
  • sweating, hot flushes/cold chills
  • trembling/shaking
  • muscle tension/aches & pains
  • Dry mouth
  • Difficulty breathing
  • palpitations
  • chest pain
  • nausea/abd distress
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2
Q

What are the cognitive symptoms of anxiety

A
  • Fear of losing control
  • feeling keyed up/on edge
  • Derealisation (feeling that objects are unreal)
  • Depersonalisation (not really here)
  • hypervigilance
  • racing thoughts
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3
Q

What are the behavioural symptoms of anxiety?

A
  • Avoiding certain situations
  • Exaggerated response to surprising events
  • Sleeping difficulty
  • Alcohol/drug abuse
  • restlessness
  • irritability
  • checking behaviours
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4
Q

What does the amygdala do?

A

assesses whether sensory material via the thalamus requires a stress/fear response. This is modified via cortically processed signal which occurs later (act first, think later)

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5
Q

What hormones are responsible for stress response?

A

catecholamines and cortisol

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6
Q

What is anxiety disorder?

A

extreme feeling of anxiousness than normal and in situations that are not normally anxiety provoking

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7
Q

What is generalised anxiety disorder (GAD)?

A

generalised and persistent anxiety in any particular environmental circumstances. It is not due to substance misuse/other medical coditions (hyperthyroidism)

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8
Q

What are the criteria for GAD?

A

-needs to be severe enough to last more than 6 days, uncontrollable and cause function impairment/distress

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9
Q

What is GAD associated with?

A
  • restlessness
  • easily fatigued
  • difficulty concentrating
  • irritability
  • muscle tension
  • sleep disturbance
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10
Q

What is typical age of onset of GAD

A

20-40 years

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11
Q

What is the course of the disorder?

A

chronic & fluctuating

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12
Q

Is GAD associated with other psychiatric disorders?

A

Yes 90% are. Eg, depression, substance abuse/other anxiety disorders

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13
Q

What is the treatment of GAD?

A
  • CBT
  • SSRI/SNRI
  • Pregabalin
  • Benzodiazepines (short term only aka 1 month)
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14
Q

What is panic disorder?

A

Recurrent attacks of severe anxiety (panics) which are not restricted to any particular situation (unpredictable)

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15
Q

What are the symptoms of panic disorder?

A

sudden onset of:

  • palpitations
  • chest pain
  • choking sensation
  • depersonalisation/derealisation
  • secondary fear of dying/ losing control/going mad
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16
Q

What may panic disorder be associated with?

A
  • Agoraphobia (fear or avoidance of places that may trigger anxiety/panic attacks)
  • depression
  • substance misuse
17
Q

What other criteria define panic disorder?

A

-not associated with substance abuse/ other medical condition

18
Q

What is the typical age of onset

19
Q

What is the biology of panic attacks?

A
  • can be triggered by infusions of lactate (by-product of muscular activity)/ rebreathing air (inc. CO2)
  • PET scan: inc metabolism of anterior pole of temporal lobe (parahippocampal gyrus)
20
Q

What is the treatment for panic disorder

A
  • CBT
  • SSRI/SNRI
  • Tricyclics
  • Benzodiazepines (short course)
21
Q

What are the 3 types of phobias?

A
  • Agoraphobia
  • social phobia
  • specific phobia
  • *(irrational fear)
22
Q

what is agoraphobia

A

Avoidance of potential phobic situations. Some people with agoraphobia experience little anxiety because they are able to avoid potential phobic situations

23
Q

What are specific phobias?

A

-Marked/persistent fear that is excessive or unreasonable (person recognises their fear as unreasonable)

24
Q

What are the treatments for specific phobias

A

behavioural therapy (exposure)

  • graded exposure/systematic desensitisation
  • CBT (if necessary)
  • SSRI/SNRI if required
25
What is social phobia?
Persistent fear of social/performance situations in which exposure to unfamiliar people occurs (more than just being shy). Occurs in relatively small social settings
26
What are the common anxiety symptoms?
- blushing/shaking - fear of vomiting - urgency/fear of micturation/defaecation
27
What is the biology of social phobia?
Increased bilateral activation of the amygdala and rCBF (regional cerebral blood flow). Normalises with treatment
28
What is the treatment for social phobia?
- CBT - SSRI/SNRI - Benzodiazepines (short term)
29
What is OCD?
Obsessional symptoms/compulsive present for at least 2 weeks and a source of distress/interference with activities
30
What is the criteria for OCD?
- obsessions must be individual's own thoughts - resistance must be present - unpleasant rituals - obsession must be repetitive
31
what co-morbidity may be present with OCD?
- schizophrenia - tourettes/other tic disorders - eating disorder - trichtillomania (pulling out hair)
32
What is the treatment for OCD?
- CBT (including response prevention) - SSRI - Clomipramine (TCA)
33
How do benzodiazepines affect anxiety?
It enhances the effect of GABA receptors(GABA-A: inhibitory ionotropic receptor). A benzodiazepine binding site is present on the GABA-A receptor.
34
What do agonists at the BZD site produce?
Relaxation and anticonvulsant effects.
35
What are the benefits of benzodiazepines?
- rapid action - well tolerated - efficacious
36
What are the problems with benzodiazepines?
- sedation & psychomotor impairment - withdrawal - dependency & abuse - alcohol interaction - can worsen co-morbid depression