Anxiolytics Flashcards

1
Q

Can BZDPNS be used as sole treatment for chronic anxiety?

A

No they should not

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2
Q

Are BZDPNs appropriate for treating depression or chronic psychosis

A

No

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3
Q

Are BZDPNs appropriate for stress related symptoms, unhappiness or minor physical disease

A

no

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4
Q

in bereavement, what effect can BZDPNs have on psychological adjustment have

A

In bereavement, psychological adjustment may be inhibited by benzodiazepines.

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5
Q

Dependence on BZDPNs is particularly likely in pt with … (3)

A

history of alcohol or drug abuse and in patients with marked personality disorders.

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6
Q

What type of symptoms do beta-adrenoceptor blocking drugs e.g. BB reduce?

A

autonomic e.g. tremor, palpitation

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7
Q

Do beta-adrenoceptor blocking drugs affect psychological symptoms of anxiety (e.g. worry, tension, fear) or non-autonomic symptoms (e.g. muscle tension)

A

No they do not reduce these.

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8
Q

BB are indicated for pt with predominantly …. symptoms

A

somatic e.g. tremor, palpitations
this may in turn prevent onset of worry and fear

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9
Q

what type of anxiety are BZDPNs indicated for

A

short-term relief of severe anxiety
avoid long term use

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10
Q

BZDPNs are indicated for short term relief of severe anxiety. what type of BZDPNs may be preferred in patients with HI?

A

shorter acting compounds
but they carry greater risk of withdrawal symptoms

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11
Q

In panic disorders (with or without agoraphobia) resistant to antidepressant therapy what can you use

A

benzodiazepine may be used; alternatively, a benzodiazepine may be used as short-term adjunctive therapy at the start of antidepressant treatment to prevent the initial worsening of symptoms.

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12
Q

The following 2 BZDPNs are occasionally administered IV for control of panic attacks

A

Diazepam or lorazepam
This route is the most rapid but the procedure is not without risk and should be used only when alternative measures have failed

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13
Q

does IM route have advantage over oral route for administration of BZDPNs

A

no

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14
Q

Buspirone is thought to act at ….

A

specific serotonin receptors

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15
Q

response to treatment with buspirone may take up to ..

A

2 weeks

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16
Q

does buspirone alleviate the symptoms of BZDPN withdrawal

A

no

17
Q

Buspirone does not alleviate the symptoms of BZDPN withdrawal. therefore what should you do about BZDPN when a pt it to take buspirone

A

pt taking BZDPN will still need to have it withdrawn gradually, usually advisable to do this BEFORE starting buspirone.

18
Q

dependence and abuse potential of buspirone

A

low

19
Q

this drug is not recommended - it is less effective than the benzodiazepines, more hazardous in overdosage, and can also induce dependence.

A

Meprobamate

20
Q

which acting barbiturates have place only in the treatment of severe intractable insomnia in patients already taking barbiturates

A

intermediate acting

21
Q

avoid intermediate-acting barbiturates in …

A

elderly

22
Q

this is a very short acting barbiturate that is used in anaesthesia

A

thiopental sodium

23
Q

thiopental sodium - use

A

very short-acting barbiturate used in anaesthesia

24
Q

Increased hostility and aggression after barbiturates and alcohol usually indicates ….

A

intoxication

25
Q

the following symptoms after barbiturates and alcohol usually indicates intoxication.

A

Increased hostility and aggression