AoS1 Flashcards
(83 cards)
Protein
A biomacromolecule which is made of a polypeptide
Biomacromoleule
A large organic molecule composed of smaller sub units found in organisms
Polypeptide
A long chain of amino acids
Proteome
All proteins that are expressed by a cell or organism at a given time
Enzyme
An organic molecule (typically a protein) that catalyzes specific reactions
Peptide hormone
a protein signaling molecule that regulates physiology or behavior
Antibody
A protein produced by plasma cells during the adaptive immune response that is specific to an antigen and combats pathogens
Amino Acids
The monomers which make up proteins
Structure of amino acids
Central carbon with an amine group, carboxyl group and an R group
Step of the polymerisation of amino acids
Condensation reaction which occurs in a ribosome
1. tRNA molecule brings the specific amino acid into place
2. the hydroxyl group is broken of the carboxyl group of one amino acid and forms a covalent bond with a hydrogen from the adjacent amino acid
3.the residue of the amino acids is joined together by a peptide bond
Polymer
a large molecule that is made of repeated monomers
Peptide bond
the chemical bond that link two amino acids
4 levels of protein structure
primary, secondary, tertiary, quaternary
Primary structure
the sequence of amino acids in a polypeptide chain
secondary structure
alpha helix, beta-pleated sheets, random coil
Alpha helix
right-hand spiraling of the polypeptide caused by the repulsion between equally charged side chains
Beta-pleated sheet
two or more lengths of polypeptide lined up beside each other forming a sheet which is held together by hydrogen bonds between non-adjacent regions of amino acids.
Tertiary structure
the overall 3D shape of a protein
Chaperon protein
a protein which folds a polypeptide
Quaternary structure
two or more polypeptides with tertiary structure joined together
Prosthetic group
a non-protein group bound to a protein with tertiary or quaternary structure
Conjugated protein
A polypeptide chain with at least tertiary structure and a prosthetic group
Nucleic Acids
A larger polymer composed from nucleotide monomers that stores genetic information
Type of nucleic acids
DNA and RNA