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Flashcards in AP Deck (23):
1

Renal Medullary Carcinoma in who

Sickle cell trait

2

Type A> thymoma

>>>>>>> spindled

3

Glomus IHC

SMA, Caldesmon

4

Clear cell sarcoma

HMB45 stronger than S100
MelanA, MiTF

5

ground glass bone Xray

Fibrous Dysplasia

6

Rheumatoid nodule

geographically demarcated zones of fibrinoid necrosis surrounded by palisading histiocytes

7

Chrondroblastoma

chicken wire calcs
plasmacytoid chondroblasts
giant cells

8

osteochondroma has connection/ maturation into the______________

medulla

9

periosteoal chrondoroma vs osteochondroma

periosteoal chrondoroma contained within the periosteum/cortex, no maturation or connection to medulla

10

angiolipoma location

volar forearm

11

Soft tissue tumors with pain

angio lipoma
angio leiomyoma

12

Myxoma syndromes?

M--> MM
Mazabraud syndrome
McCune-Albright syndrome

13

Schwannoma

dilated vessels with hyalinized, thick walls

14

PMT

reminiscent of hemangiopericytoma (HPC), but additionally it may contain areas of cartilaginous metaplasia with “grungy” calcification, adipose and fibrous tissue, and osteoclastlike multinucleated giant cells

15

Cellular angiofibroma

vulvovaginal, inguinal, and paratesticular regions

milk line

just like mammry type myofibroblastoma

ER PR pos

16

One consistent UPH marker

vimentin

17

UPS vs MFS

UPF = Vimentin
MFS = vimentin + SMA

18

NF stains

s100 (schwann)
NF (axons)
34 (stromal)
EMA/GLUT1 (peineureum)

19

Myofibroma

subcut
ZONAL on low

20

uveal melanoma and blue nevus share what?

same mutation - GNAQ

21

Pemphigus Vulgaris

PV--> V3 --> desmogelin 3

22

Pemphigus follieaceous

floats to the top so is #1 --> Desmogelin 1

23

differentiate b/w aggressive angiomyxoma, cellular angiofibroma and angiomyofibroblastoma

aggressive angiomyxoma = has muscular vessels = desmin, SMA pos

cellular angiofibroma = thinner vessels = starts with angio = CD34 pos

angiomyofibroblastoma = Desmin pos, SMA neg