Aphasia Flashcards

1
Q

Aphasia and localization of function

A

with basic knowledge of the brain: cellular and anatomical levels, electrochemical processes, awareness of subcortical areas

  • one can embark on studying language and the brain via aphasiology
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2
Q

Aphasia

A

loss of language due to brain disorders

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3
Q

Classifications of aphasia (2) based on what?

A

fluent, nonfluent. Based on expressive language

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4
Q

Expressive language - signs of aphasia

A

rate, effort (does it look like they’re struggling?), length (of utterances), form (is there grammatical inflexions)

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5
Q

Paul Broca findings

A

Encountered patient with intact comprehension, but little or not speech output. All patients had lesions: at posterior of the third convolution in the LH. Broca found language was localized in the left hemisphere

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6
Q

Damage to Broca’s area

A

Broca’s aphasia. Marked by impaired, halting, agrammatic output. Non-fluent, expressive aphasia

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7
Q

Agramatic

A

omission of articles, auxiliary verbs, word endings

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8
Q

Carl Wernicke

A

Left posterior section of the superior temporal gyrus; auditory cortex below the Sylvian fissure

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9
Q

Wernicke Aphasia

A

“fluent” aphasia. Fluent, yet often meaningless output (programmatic speech); impaired comprehension: receptive aphasia. Wernicke’s is to content/semantics as Brocas is to form. Self-awareness varies. Happy or loopy without self-awareness.. Suicidla if aware. Receptive aphasia, production deficit

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10
Q

Third aphasia, condition aphasia

A

intact comprehension and fluency; disproportionate difficulty with repetition, request anomia. Conduction aphasia presumed to be due to samage to arcuate fascicles (tract connecting areas) - 2 possible lesion sites (arcuate fascicles, areas of auditory cortex and underlying white matter

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11
Q

Written language in aphasia

A

often mirrors oral language. Broca’s: reading for comprehension spared; difficulty writing.

Wernicke’s: may be able to read about and write, but comprehension/content in writing impaired, but deficits more variable than in oral language

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12
Q

Global Aphasia

A

global impact bc you have widespread damage in the local hemisphere

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13
Q

House - Aphasias #1-7

A

1) Broca’s Aphasia
2) Wernicke’s Aphasia
3) Conduction aphasia
5) Subcortical motor aphasia
7) Subcortical sensory aphasia
4) Transcortical motor aphasia
6) Transcortical sensory aphasia

4) and 6) are still theoretical in nature, associated with diverse damage to different parts of the brain at the same time

8) Global aphasia

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14
Q

ais anomia an aphasia

A

an impairment of the process of retrieving words form one’s lexicon. Also referred to as lexical retrieval deficit. Anaphase subtype or a symptom of many aphasia? Present in many aphasias; hence related to damage in many brain areas. Something about our lexicaon is not super localized/

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15
Q

3 hypothesized mechanisms for anomia1

A

1) damage neuronal representations
2) delay or failure of intact representations to reach threshold
3) failure to inhibit related entries

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16
Q

Naming error types (4)

A

1) slowed/delayed activation
2) circumlocution (retrieval failure)
3) unrelated word retrieved
4) semantic paraphasia (when someone says a word semantically related to the word they want to say)
5) phonemic paraphasia (starts or ends with same phoneme, or rhymes)

17
Q

Lesion sites for anomia

A

much variability here. Frontal lobe; temporal lobe; subcortical. Also large areas of damage in temporoparietal cortes. Why? Our lexicon is not localized - because lexical entries have phonological representation, orthographic representation, semantic representation

18
Q

MRI/fMRI

A

functional magnetic resonance imagine

19
Q

CT

A

computed topography

20
Q

CAT

A

computed axil tomography - x-ray

21
Q

PET

A

positive emission tomography - radioactive chemical tracers injected into blood stream