Apoptosis and Necrosis Flashcards Preview

Biochemistry (III) > Apoptosis and Necrosis > Flashcards

Flashcards in Apoptosis and Necrosis Deck (14)
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1
Q

________: Programmed Cell death

A

Apoptosis

2
Q

______ and ________ are the two general forms of cell death.

A

Apoptosis and Necrosis

3
Q

_________ is programmed, whereas ______ is more incidental and can occur due to unintended damage.

A

Apoptosis

Necrosis

4
Q

What are 2 times that one might expect to see apoptosis occur?

A

1) During Embryonic Development

2) During Immune System Development

5
Q

During embryonic development or immune system development, one might expect to see __________ occur during the process.

A

Apoptosis

6
Q
Necrosis is \_\_\_\_\_\_\_\_\_\_\_\_ pathological.
A) Rarely
B) Sometimes
C) Always
D) Never
A

C) ALWAYS

7
Q

This apoptotic pathway is initiated by interior signaling due to irreparable, irreversible DNA damage.

A

Intrinsic apoptotic pathway

8
Q

This apoptotic pathway is initiated by exterior signals due to indications of damage or infection.

A

Extrinsic Apoptotic Pathway

9
Q

What is cell ‘blebbing’?

A

When a cell disintegrates into small vesicles and are taken up by phagocytosis.

10
Q

________ destroy proteins and other molecules within the cell during apoptosis.

A

Caspases

11
Q

This form of apoptosis is caspase-independent.

A

AIF-Apoptosis-Inducing Factor

12
Q

This form of apoptosis will invade the nucleus, initiate chromatin development, and clip the ‘beads on a string’ and then bleb out.

A

AIF-Apoptosis

13
Q

Increasing ______ ________ drives the pH down denaturing proteins leading to the collapse of the cell membrane and causing necrosis.

A

Lactic acid

14
Q

Lysosomal hydrolytic enzymes will inappropriately clip up stuff after necrosis and you will see an __________ response. This type of response can lead to the development of _________.

A

Inflammatory

Cancer (because inflamed cells are less likely to initiate apoptosis)