Approach to chronic diarrhoea and constipation Flashcards

(37 cards)

1
Q

List the 6 steps in the approach to diarrhoea

A
  1. History & physical examination
  2. Symptomatic therapy
  3. Laboratory investigations
  4. Diagnostic imaging
  5. Gastrointestinal biopsy
  6. Therapeutic trials
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2
Q

List the DDx for alimentary diseases that cause diarrhoea

A
  • Adverse reactions to food: allergy, poisoning
  • Inflammatory bowel disease
  • Antibiotic responsive diarrhoea
  • Lymphangiectasia
  • Lymphoma/tumours
  • Infectious diarrhoea
  • Obstructions
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3
Q

What is Lymphangiectasia?

A

Lymphatic system within the SI is obstructed -> dilation of the lacteal
Diarrhoea due to protein loss into the intestine

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4
Q

List the DDx for systemic causes of diarrhoea

A

Liver disease
Renal disease
Pancreatic disease
Endocrine disease
- Addison’s disease
- Diabetes mellitus
- Hyperthyroidism

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5
Q

Describe the information which should be gathered when you are presented with a dog with diarrhoea

A

Gastrointestinal signs
Systemic signs
Diet history
Vaccine history etc
Verify vomiting vs regurgitation
Classify the diarrhoea - SI vs LI
Grade the severity of signs

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6
Q

Why should you check the tongue in the physical exam?

A

To check for a linear foreign body

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7
Q

Define haematochezia

A

Fresh blood in the stool

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8
Q

Why is it important to classify diarrhoea? How is this done?

A
  • Helps with localisation
  • Ask owner to bring in a sample of faeces
  • Photo of the faeces
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9
Q

Describe the features of diarrhoea and clinical signs that enable it to be localised to the small intestine

A
  • Increased volume
  • Colour change
  • Normal to slight increase in frequency
    ± Weight loss
    ± Flatulence, borborygmi, halitosis
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10
Q

Describe the features of diarrhoea and clinical signs that enable it to be localised to the large intestine

A
  • Decreased volume
  • Increased frequency
  • Urgency & tenesmus
  • Mucus & haematochezia
  • Dyschezia: pain on defaecation
  • Constipation ± variable consistency
  • No weight loss?
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11
Q

What is the main function of the LI?

A

To act as a storage organ for appropriate defaecation, enabling the individual to make a conscious decision on when to defecate

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12
Q

Describe diffuse diarrhoea

A

Watery with some solid components
Fresh blood

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13
Q

Melaena is a sign of…?

A

Upper GI disease
Blood loss from stomach or SI -> blood gets digested
Dark stool – tar/black

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14
Q

Fibre supplementation is used for diarrhoea localised where?

A

Large intestine

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15
Q

How should a patient be managed/prepared before a colonoscopy?

A

Starve 48 hours
Poly-ethylene glycol:
- 3 doses, 4h apart
- Use Stomach tube
Followed by 2x warm water enemas

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16
Q

Which laboratory test is carried out first in diarrhoea cases?

A

Faecal analysis

17
Q

What is being assessed on faecal analysis?

A

Parasites
Bacteria

18
Q

Name 3 parasites which may be seen on a faecal analysis

A
  • Giardia
  • Cryptosporidia
  • Tritrichomonas foetus (cats)
19
Q

Describe the disease caused by Tritrichomonas foetus

A
  • Poor bodily condition
  • Chronic diarrhoea
  • Most commonly affects pedigree cats and cats in colonies
  • Causes SI diarrhoea in cats and LI diarrhoea in dogs
20
Q

How is Tritrichomonas foetus diagnosed?

A

Faecal preparation in saline
Culture
Polymerase chain reaction

21
Q

Describe the stage 2 laboratory tests carried out for diarrhoea cases

A

Haematology
Serum biochemistry
Urinalysis
Mainly used to rule out systemic diseases - Liver disease, Kidney disease, etc

22
Q

Describe the endocrine tests used in diarrhoea cases

A

ACTH stim test/ Basal cortisol - hypoadrenocorticism
Total thyroxine - hyperthyroidism

23
Q

What is the trypsin-like immunoreactivity test used for?

A

Exocrine pancreatic insufficiency

24
Q

Which test could you carry out to diagnose pancreatitis?

A

Total lipase or pancreatic lipase

25
Folate and cobalamin tests are used to assess?
Malabsorption
26
What does a hypocobalaminaemia result indicate?
A negative prognostic indicator If present treat with cobalamin
27
In cases of diarrhoea when is radiography useful?
Radiography is good for: - Foreign bodies - Masses - Obstructions
28
In cases of diarrhoea when is ultrasound useful?
Can identify intestinal masses and lymph nodes
29
Describe how endoscopy is used in diarrhoea cases
Minimally invasive and direct examination Requires equipment and expertise Small superficial samples from a limited region Harder to find a focal lesion Smaller biopsy samples
30
Describe how a coeliotomy is used in diarrhoea cases
Can get multiple full-thickness biopsies Surgical risk Best for cats
31
A non-specific normal /mild inflammation result from a biopsy indicates what possible causes?
Adverse reaction to food Antibiotic-responsive diarrhoea etc IBD ~ “chronic enteropathy”
32
A moderate-severe inflammation result from a biopsy indicates what cause?
IBD ~ “chronic enteropathy”
33
Which two specific severe conditions can also be diagnosed from a biopsy?
Lymphoma Lacteal dilation - Lymphangiectasia
34
What information would you ask owners to record in a diary?
Frequency of diarrhoea Other signs – vomiting / pain Appetite and demeanour Compliance with treatment
35
Define constipation
Difficult, incomplete, or infrequent evacuation of dry hardened faeces from the bowels
36
List the possible causes of constipation
- Dietary - Neuromuscular: idiopathic megacolon - Obesity - Hospitalisation - Change in routine - Inactivity - Colonic obstruction: stricture, pelvic trauma, neoplasia - Dehydration - Drug-induced
37
How is constipation treated?
- Remove underlying cause if possible - Oral laxatives i.e. lactulose - Enemas - Oral polyethylene glycol - Gentle manual evacuation under anaesthetic - Surgery (if megacolon) - Dietary management: High fibre diet