ASAP V2 Flashcards
(156 cards)
Tunica Intima
Innermost layer of blood vessels, composed of endothelial cells, providing a smooth surface for blood flow.
Tunica External
Outermost layer of blood vessels, composed of connective tissue, providing support and protection to the vessel.
Tunica Media
Middle layer of blood vessels, primarily consisting of smooth muscle cells, responsible for vessel tone and diameter regulation.
Elastic vs Musuclar arteries
Elastic closer to heart, larger, higher elastin content
Muscular have internal elastic laminar and assists in directing blood flow to regions
3 arteries off the aortic arch
Brachiocephalic
left common Carotid
left Subclavian
Haemostasis
1.vasoconstriction to reduce blood flow
2.formation of temporary platelet plug at injury site
3.coagulation cascade
4.Fibrinolysis, clot dissolves after tissues repaired
Haematopoiesis (formation of blood cells)
-Occurs in red bone marrow (soft,spongy bone in middle)
Blood flow through heart
SVC/IVC
Right atrium
Tricuspid valve
Reign ventricle
Pulmonary valve
Pulmonary artery
Lung
Pulmonary vein
Left atrium
Mitral Valve
Left ventricle
Aortic valve
Aorta
Layers of heart
Endocardium (innermost)
Myocardium (middle muscular layer)
Epicardium (CT for lubrication and protection)
Conduction system of the heart
-SA node=natural pace maker causes atria contractions
-AV node=delays signal from SA then ventricle contraction
-Bundle of His= pathways for electrical signals to travel from AV node to ventricles
-Purkinje fibres= terminal branches of bundle of his
Starling forces
Capillary/Hydrostatic (pressure exerted by fluid in capillary outwards)
Interstitial (pressure exerted by fluid outside capillary, inwards)
Plasma Colloid Osmotic (pressure exerted by proteins such as albumin pulling fluid towards capillary)
Interstitial fluid colloid osmotic (pressure exerted by proteins such as albumin pulling fluid towards the interstitial fluid)
Hormonal extrinsic pathway of cardiac regulation
-Adrenaline and noradrenaline released from adrenal medulla and bind too extracellular receptors on the surface of target cardiac cells
-target cells initiate a response acting to increase of decrease cardiac function
-stimulation of sympathies nerves innervating the adrenal medulla results in the released of adrenaline (80%) and noradrenaline (20%)
-stimulates alpha receptors within blood vessels and beta receptors in the myocardium, having a chronotropic (Heart beats with less force) or ionotropic (heart beats with more force)
Aortic murmurs
Where, When, what
2nd ICS, right sternal adge
Aortic regurgatation - blowing diastolic mumrmur
Aortic stenosis- high pitched, midsystolic (can cause dyspnea, and angina)
Mitral stenosis and regurgitation
5th ICS midclavicular line
Stenosis- low pitched mid diastolic murmur loudest over apex
Regurgitation- systolic murmur heart at apex
Where to Ausculate pulmonary valve
2nd ICS left sternal edge
Where to ausculate tricuspid valve
4th ICS left sternal edge
Cardiac output at rest
4-5L/min
Cumulative incidence
Number of new events divided by total population at risk
Respiratory membrane/blood air barrier
Fused basal lammina between two pops of epithelial cells, the alveolar epithelium and endothelium of pulmonary cavities
Anatomical dead space resp
Where gas exchange does not occur
Tidal volume, total ventilation
Tidal volume is the amount of air that is inhaled or exhaled
Total ventilation is volume of air moved per minute (tidal volume times resp rate)
Peptide hormones
-short Half life
-bind to cell surface receptors
Steroid hormones
-derived from cholesterol
-made in smooth ER and mitochondria
-not stored
-longer half life
-modulate gene expression (by activating or repressing gene transaction)
Amine hormones
-Amino acid derived
-Stored in vesicles until needed
-short half life
-cell surface receptors