ASD

Question 1

prognosis

Answer 1

gaurded
small proportionno longer meet dx when older
1-2% normal life
5-20% borderlinenormal life
2/3 remain severely handicapped
30% develop sz later
IQ, language and after that support improves prognosis

Question 2

ASD numbers

Answer 2

1/68
males 4 timesmore likely
20% havesz (30% of MR in general have sz)
30% have MR
50% meet crteria for ADHD, but think of developmental level.
5% have cytogenic abnormalities
rate in siblings is 10%
heritability is 90%

Question 3

Medsin ASD

Answer 3

Risoerdal and Abilify approved for irritaility and there is a good response > 50%
ritualistic behaviour not treated by SSRIs (-ve chochrane review)
Haldo l and Risperdal my help with repetetive behaviours

Question 4

TD Tx

Answer 4

SGA
another SGA
Clozapine
Suppression with SGA+ FGA
FGA alone
Tetrabenazine
donepezil
melatonin
Vit B6
Vit E
branched chain amino acids