aseptics

Question 1

why use 3

Answer 1

• versatility of dose and administration
• safety of staff
• safety for patients

Question 2

3 ppl things made

Answer 2

• chemotherapy
• radiopharmaceutical
• total parenteral nutrition

Question 3

enteral and parenteral meaning

Answer 3

enteral
of or relating to the intestines

parenteral
introduced other than by way of the intestines

Question 4

medicine act 1968, section 10, expiriary, who amke, what need to make, whoc an release, do they get auditied

Answer 4

• max 7 day expiry
• items prepared directly supervised by a pharmacist
• product preparation for a specific patient in accordance with a prescription
• products released by an appropriately trained pharmacist
• local/reginal audit

Question 5

2 types of non-viable

Answer 5

• particulates
• chemicals

Question 6

4 types of viable

Answer 6

• bacteria
• fungi
• viruses
• toxins

Question 7

6 effects of contamiantes

Answer 7

chemical composition
pH - ionise med/pain
sterility
pyrogenicity
bio or therapeutic potency
physical appearance
particulate matter

Question 8

2 types of isolaters and cabinets

Answer 8

laminar flow cabinets
positive/negative pressure isolators

Question 9

2 reasons why use isolaters

Answer 9

provide an enclosed environment
sperate operators form their environment

Question 10

what is the main function of laminar flow, and what does it do

Answer 10

laminar flow cabinets
provide unidirectional stream of filtered air
protecting the product form contamination

Question 11

4 step process of how lamianr cabinet works

Answer 11

dirty air entered the air cleaner
air is processed through pre-filter where some particles are absorbed
air is purified through a final HEPA filter
clean air is discharged into the work area creating a positive pressure laminar flow hood

Question 12

2 types of laminar flow and theur use

Answer 12

horizontal → for dispensing of non hazardous products (parenteral nutrition)

vertical - for products hazardous to the operator (contain products in container)

Question 13

2 types of isolators

Answer 13

positive pressure, high pressure inside which pushes air out
negative pressure, low pressure pulls air in, toxic products

Question 14

4 ways HEPA filter works

Answer 14

interception
impaction
diffusion
sieving

Question 15

4 physicla test

Answer 15

status of room
glove leak test
room air change rate
particle count
pressure and filter status of LAFC
LAFC/isolator velocity

Question 16

4 microbiological tests

Answer 16

settle plates
contact plates
swabs
finger dabs
active air samples