Aspirin

Question 1

What is the mechanism of action of Aspirin?

Answer 1

●Non-steriodal anti-inflammatory drug (NSAID).
●Has antiplatelet, antipyretic, anti-inflammatory, analgesic effects. Only given by ambulance personnel for Antiplatelet activity.
●Inhibits (blocks) the enzyme clycooxgenase which results in a reduction of the formation of prostaglandins and thromboxane.

Question 2

What are the indications for Aspirin?

Answer 2

●Myocardial Ischaemia.
●STEMI.

Question 3

What are the contraindications of Aspirin?

Answer 3

●Known severe allergy.
●Third trimester of pregnancy.

Question 4

What are the cautions for Aspirin?

Answer 4

●Known bleeding disorder (will increase risk of bleeding.)
●Clinically significant bleeding.
●Known worsening of bronchospasm with NSAIDs.

Question 5

What is the adult dose of Aspirin?

Answer 5

●300mg once

Question 6

What are the side effects of Aspirin?

Answer 6

●Increased bleeding.
●GI ulcers or bleed (associated with long term use.)