Aspirin

Question 0

Class?

Answer 0

Analgesic
Antipyretic
Anti-inflammatory

Question 1

Generic name?

Answer 1

Acetylsalicylic Acid, Aspirin, ASA

Question 2

Mechanism of action?

Answer 2

Small doses aspirin blocks thromboxane A2, a potent platelet and vasoconstrictor.
Decreased platelet aggregation.
Used in acute phase of management of myocardial infarction.

Question 3

Indications?

Answer 3

Chest Pain or signs/symptoms of acute myocardial infarction.
ECG changes suggestive of acute myocardial infarction.
Unstable Angina.
Pain, Discomfort, fever in adult patient only.

Question 4

Contraindications?

Answer 4

Bleeding ulcer, hemorrhagic states, hemophilia.
Known hypersensitivity to salicylates or other non-steroidal anti-inflammatories that has led to hypotension and/or bronchospasm.
Children & adolescents

Question 5

Side Effects?

Answer 5

Caution with history of asthma. Anaphylactic reactions in sensitive patients have occurred.
Skin Eruptions

Question 6

Dosage?

Answer 6

Cardiac: 160-325mg (2-4 pediatric chewable tabs) chew or swallow.
Pain/Discomfort/Fever: 325mg PO

Question 7

Effects?

Answer 7

Onset: 20-30 minutes
Peak effects: 2 Hours
Duration of Action: 4-6 Hours
- Heat & light sensitive, odor of acetic acid (vinegar) indicates degradation of product