Aspirin Flashcards
1
Q
Presentation
A
300mg chewable tablets
2
Q
Pharmacology
A
An analgesic, antipyretic, anti-inflammatory and antiplatelet aggregation agent
Actions;
To minimise platelet aggregation and thrombus formation in order to retard the progression of coronary artery thrombosis in ACS
Inhibits synthesis of prostaglandins - anti-inflammatory actions
3
Q
Metabolism
A
Converted to salicylate in the gut mucosa and liver; excreted mainly by the kidneys
4
Q
Indications
A
ACS
5
Q
Contraindications
A
Hypersensitivity Actively bleeding ulcer Bleeding disorder Chest pain psychostimulant OD with BP >160 Suspected dissecting AAA
6
Q
Precautions
A
Peptic ulcer
Asthma
Pts on anticoagulants
7
Q
Route of admin
A
Oral
8
Q
Side effects
A
Heartburn, nausea, GI bleed
Increased bleeding time
Hypersensitivity reactions
9
Q
Special notes
A
Lasts for the natural life of the platelets
Duration: 8-10 days
