Associations

Question 1

ABDOMINAL PAIN + DIARRHEA + LEUKOCYTOSIS + Recent antibiotic use

Answer 1

C. DIFF INFECTION

Question 2

ACHILLES TENDON XANTHOMA

Answer 2

Familial HL

Decreased LDL-R signaling

Question 3

ADRENAL HEMORRHAGE + HYPOTENSION + DIC

Answer 3

Waterhouse-Friderichsen Syndrome (Meningococcemia - N. meningitidis)

Question 4

ANAPHYLAXIS (Pulmonary Sx) FOLLOWING BLOOD TRANSFUSION

Answer 4

IgA DEFICIENCY - Mucosal surfaces

Question 5

ANTERIOR “DRAWER SIGN” - Subject sits supine with legs bent 90deg, examiner sits on subject’s feet, place thumbs on proximal tibia and push anteriorly

Answer 5

ANTERIOR CRUCIATE LIGAMENT INJURY

Question 6

ARACHNODACTYLY (spider fingers) + UPWARD LENS DISLOCATION + AORTIC DISSECTION + HYPERFLEXIBLE JOINTS + HIGH ARCHED PALATE with crowded teeth

Answer 6

MARFAN SYNDROME (Defect of FIBRILLIN)

Question 7

ATHLETE with POLYCYTHEMIA

Answer 7

Secondary to EPO injection

Question 8

BACK PAIN + FEVER + NIGHT SWEATS

Answer 8

POTT DISEASE (vertebral TB)

Question 9

BILATERAL ACOUSTIC SCHWANNOMAS

Answer 9

NF TYPE 2

Question 10

BILATERAL HILAR ADENOPATHY + UVEITIS

Answer 10

SARCOIDOSIS (NON-CASEATING GRANULOMAS)

Question 11

BLACK ESCHAR on pt’s face + DIABETIC KETOACIDOSIS

Answer 11

MUCOR or RHIZOPUS fungal infection

Question 12

BLUE SCLERA due to exposure of choroidal veins

Answer 12

OSTEOGENESIS IMPERFECTA (Type I collagen defect)

Question 13

BLUISH LINE ON GINGIVA

Answer 13

BURTON LINE (Lead poisoning)

Question 14

BONE PAIN + BONE ENLARGEMENT + ARTHRITIS

Isolated Increase in ALP

Answer 14

PAGET DISEASE OF BONE (Osteoclastic, Mixed osteoclast/osteoblast, Osteoblastic)

Question 15

BOUNDING PULSES + WIDE PULSE PRESSURE + DIASTOLIC HEART MURMUR + HEAD BOBBING

Answer 15

AORTIC REGURGITATION

Question 16

BUTTERFLY FACIAL RASH (sparing nasolabial folds) + RAYNAUD in YOUNG FEMALE

Answer 16

SLE

Question 17

CAFE AU LAIT SPOTS + LISCH NODULES (Iris hamartoma) + CUTANEOUS NEUROFIBROMAS + PHEOCHROMOCYTOMA + OPTIC GLIOMA

Answer 17

NF TYPE 1

Question 18

CAFE AU LAIT (UNILATERAL) + POLYOSTOTIC FIBROUS DYSPLASIA + PRECOCIOUS PUBERTY + Multiple ENDOCRINE abnormalities

Answer 18

McCUNE-ALBRIGHT SYNDROME (Mosaic G-protein signaling mutation)

Question 19

CALF PSEUDOHYPERTROPHY

Answer 19

Muscular Dystrophy (most commonly DUCHENNE - X-linked recessive frameshift mutation of DYSTROPHIN gene)

Question 20

CERVICAL LAD + DESQUAMATING RASH + CORONARY ANEURYSMS + RED CONJUNCTIVAE/TONGUE + HAND-FOOT CHANGES
What is the Tx?

Answer 20

KAWASAKI DISEASE

Tx: IVIG + Aspirin

Question 21

CHERRY RED SPOTS on macula

Answer 21

TAY-SACHS (ganglioside accumulation)
NIEMANN-PICK (sphingomyelin accumulation)
Central Retinal artery occlusion

Question 22

EXERTIONAL CHEST PAIN

Answer 22

ANGINA (Stable: With moderate exertion; Unstable: With minimal exertion or at rest)

Question 23

CHEST PAIN + PERICARDIAL EFFUSION/FRICTION RUB + PERSISTENT FEVER following MI

Answer 23

DRESSLER SYNDROME (Autoimmune-mediated post-MI fibrinous pericarditis - 2wks to several months post-acute episode)

Question 24

CHEST PAIN + ST DEPRESSION on EKG

Answer 24

UNSTABLE ANGINA (- Troponins)
NSTEMI (+ Troponins)

Question 25

Child uses ARMS to stand up from SQUAT

Answer 25

DUCHENNE MUSCULAR DYSTROPHY (GOWERS SIGN)

Question 26

Child with FEVER later develops RED RASH on FACE that spreads to BODY

Answer 26

ERYTHEMA INFECTIOSUM/FIFTH DISEASE | Slapped cheeks appearance by PARVOVIRUS B19

Question 27

CHOREA + DEMENTIA + CAUDATE DEGENERATION | What is the etiology?

Answer 27

``` HUNTINGTON DISEASE (Autosomal dominant CAG repeat expansion) ```

Question 28

CHORIORETINITIS + HYDROCEPHALUS + INTRACRANIAL CALCIFICATIONS

Answer 28

CONGENITAL TOXOPLASMOSIS

Question 29

ABDOMINAL PAIN + ASCITES + HEPATOMEGALY

Answer 29

BUDD-CHIARI SYNDROME (post-hepatic venous thrombosis)

Question 30

POUCH MNEMONIC (Rejoy)

Answer 30

[FIRST =Ears] [SECOND= Tonsils] [THIRD = Bottom to - Inferior parathyroid + Thymus] [FOURTH - Top (superior parathyroid]

Question 31

AORTIC ARCH DERIVATIVES MNEMONICS: REJOY

Answer 31

Max HaS CAROTIDS [leaned from Anatomy and Physiology] - MHSCAP 1st arch: Maxillary artery 2nd arch: Hyoid and Stapedial 3rd arch: Common carotids, Internal carotid root 4th arch: Aorta, right subclavian (branch of aorta) 6th arch: Pulmonary Trunk + Ductus arteriosus (connects to aorta)