Asthma Flashcards

1
Q

Reversible chronic inflammatory airway disorder, characterized by increased responsiveness of the tracheobronchial tree to various stimuli resting in episodic reversible narrowing of the airway

A

Asthma

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2
Q

Most common type of asthma

A

occupational

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3
Q

Which immune responses are responsible for the development of asthma?

A

Th1 type and Th2 type cytokine response.

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4
Q

Th1 type does what

A

fights infection

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5
Q

Th2 type immune response does what

A

contributes to the development of asthma

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6
Q

Inducer stimuli that cause inflammation are

A
  1. inhaled allergens
  2. low molecular weight sensitizers
  3. viral of mycoplasmal respiratory infections
  4. noxious gases
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7
Q

Which inducers cause asthmatic bronchoconstriction

A
  1. Exercise
  2. Cold air
  3. laughter
  4. emotional upset
  5. inhaled irritants
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8
Q

What are triggers responsive for sudden severe bronco constriction

A
  1. Acetylsalicylic acid
  2. non steroidal antiinflammatory drugs
  3. B-adrenergic blockers
  4. food allergies
  5. certain food additives
  6. stings
  7. bites
  8. injections
  9. inhaled allergens
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9
Q
What type of asthma is this:
Symptoms <2 days a week
night-time <2 times/month
SABA use <2/days week
effect on normal activity none
Lung function test Normal FEV > 80% FEV/FVC normal
A

Intermittent asthma

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10
Q

Symptoms: > 2 days a week/not daily
nighttime 3-4 times/month
SABA use: >2 days/week not daily and not more than once on any day
Effect on activity: minor limitation
Lung function test: FEV >80% of predicted value
FEV/FVC normal

A

mild persisten asthma

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11
Q

Symptoms: daily
night time awakening: once a week not nightly
SABA use: daily
Effect on activity: some limitation
Lung function: FEV > 60% but less than 80%
FEV/FVC reduced

A

moderate

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12
Q
Symptoms: throughout the day
night time: often 7 times a week
SABA use: several times a day
Effect on function: severe limitation
lung function: FEV <60% FEV/FVC reduced
A

severe

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13
Q

What are possible co-morbidities for asthma

A
  1. Glaucoma
  2. HTN
  3. GERD
  4. DM
  5. Arthritis
  6. Neoplasm
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14
Q

Are serum IgE levels decreased or increased with patients with asthma

A

Total IgE is elevated in people with asthma which is associated with disease severity

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15
Q

Why does the color of the patients sputum change during an asthma attack

A

Eosinophil peroxidase

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16
Q

What are the causes of PNA

A
  1. Fungal
  2. Bacterial
  3. Viral
17
Q

Which breath sounds are likely to be heard while assessing for PNA?

  1. Bronchial breath sounds
  2. Egophony
  3. Bronchial breath sounds and egophony?
  4. Rales
A
  1. Bronchial breath sounds and egophony
18
Q

How is PNA caused by mycoplasma treated?

A

Macrolide antibiotics

19
Q

Pneumonic for treating mycoplasma PNA

A

Mycoplasma
Atypical
Mild symtoms
Macrolide

20
Q

What are the two main types of asthma medications?

A
  1. Controller

2. Reliever

21
Q

What are the types of controller asthma medications?

A
  1. ICS

2. Long acting beta agonist bronchodilator

22
Q

What are add on controller asthma medications?

A
  1. Anticholinergic
  2. Anti IgE
  3. Anti-IL5
  4. Systemic cortico steroids
23
Q

List asthma reliever medication names

A
  1. Short acting B2 agonist bronchodilators
  2. low-dose ICS fomoterol
  3. Short acting anticholinergics
24
Q

Which step is this?
High dose IGC + LABA+oral glucocorticoid
no alternative
SABA

25
What step in asthma treatment is this? High-dose IGC+LABA SABA
Step 5
26
Asthma treatment which is this? Medium dose IGC +LABA Alt Medium-dose IGC+ either LTRA, theophylline or Zileuton
Step 4
27
This is step what? Low-dose IGC + LABA or medium dose IGC Low-dose IGC + either LTRA, theophylline, or Zileuton
Step 3
28
This is what step in the asthma treatment stepwise approach? Low dose IGC Alt Cromolyn, LTRA or theophylline
Step 2
29
No daily medication needed | Saba this is step number?
Step 1
30
Regular low dose ICS is the recommendation for what types of patients?
Regular low dose ICS is recommended for all patients with asthma who have symptoms more often than twice a month, waking with asthma more than once a month and any asthma symptoms plus risk factor exacerbations
31
A patient with seasonal asthma, what is the ideal treatment for seasonal allergic asthma?
start ICS immediately upon onset of symptoms and discontinue 4 weeks after exposure ends
32
When should asthma be treated with an antibiotic?
1. Fever 2. Purulent sputum 3. evidence of pneumonia 4. Bacterial sinusitis
33
What is the purpose of peak flow in patients with | Periodic severe asthma exacerbations
The purpose of peak flow monitoring is to help asthma patients follow their disease and predict exacerbations , triggers and response to treatment
34
Zone Green is what in the asthma chart
1. PEF measurement is at least 80