ATIBIOTICS

Question 1

What drugs are given as an initial loading dose followed by a maintenance dose?

Question 2

“Label” or “Sig:”

Antibiotic prescription

Answer 2

the prescriber’s directions to antibiotics vs analgesics
Label:english
Sig.: Latin

Question 3

***What are antibiotic regimens in dental infection ? vs. Prophylaxis ?

Antibiotic prescription

Answer 3

Dental infection:
short‐term therapy: 3-5 days (high dose)
Long-term therapy: 7-10 days (low dose)
Prophylaxis:
30-60 mins before surgery
dose: up to 2g

Question 4

Common antibiotic groups in dentistry

Antibiotics in Dental infections

Question 5

Doses of common antibiotics in dentistry

Question 6

Frequency of common antibiotics in dentistry

Question 7

What are 2 general ways antibiotics work?

Answer 7

Bactericidal
Bacteriostatic

Question 8

Latin Abbreviations of frequency
(stat?)

Question 9

p.r.n? p.o? sig? disp?

Question 10

***Give an example of instructions to patient for Azithromycin

Question 11

First choice? If first line fails? if allergy?

Antibiotic selection algorithm for dental infection

Question 12

(3 scenarios)

When are antibiotics indicated in an endodontic infection?

Question 13

***What is the proper duration of antibiotic treatment for dental infections?

Question 14

What is the antibiotic of choice for an acute apical abscess?

ANTIBIOTICS FOR ENDODONTIC INFECTIONS

Question 15

Loading dose: meaning? mg? effect?

Question 16

Why is clindamycin recommended for patients allergic to penicillin? But not for prophylaxis

ANTIBIOTICS FOR ENDODONTIC INFECTIONS

Question 17

systemic signs and symptoms of infection or spread of infection?9

ANTIBIOTICS FOR ENDODONTIC INFECTIONS

Answer 17

○ increased swelling,
○ malaise,
○ fever >37.8 °C (100 °F),
○ trismus
○ lymphadenopathy,
○ cellulitis,
○ osteomyelitis
○ persistent infection or
○ Persistent exudation after RCT

Question 18

immunocompromised patients?

ANTIBIOTICS FOR ENDODONTIC INFECTIONS

Answer 18

1. Uncontrolled metabolic diseases - usually poorly controlled Insulin dependent diabetic patient
2. AIDS
3. Cancer (Advanced stages of leukemia and lymphomas)
4. 1 year after radiotherapy and chemotherapy
5. Organ transplant
6. under immunosuppressive medication (cyclosporine, methotrexate)
7. Patient with end stage renal disease

Question 19

Why using systemic antibiotics in periodontal infections?

ANTIBIOTICS FOR PERIODONTAL CONDITIONS

Answer 19

Antibiotics immediately after scaling and root planing can provide more probing depth reduction and gain of attachment with healing improved up to six months.

Question 20

Periodontic Classification

When are antibiotics indicated in an periodontal infection?

Question 21

What are necrotizing periodontal diseases (NPDs)

Answer 21

NPDs are bacterial infections caused specifically by Treponema spp., F.
nucleatum, and P. intermedia.

Question 22

What is the antibiotic of choice for Necrotizing Periodontal Diseases?

Answer 22

metronidazole (250 mg three times a day for seven days)

Question 23

Which drug exets anticollagenase effect?

Answer 23

Doxycycline

Question 24

What are topical antimicrobilas? Indications?

Answer 24

chlorhexidine gluconate

Question 25

2 groups

Which patients require antibiotic prophylaxis?

Question 26

What are high risk pts of Endocarditis?

ANTIBIOTIC PROPHYLAXIS

Question 27

What are immunocompromised pts?

Question 28

First choice? If allergy type I? If allergy type IV? Adutls/ Kids?

what are the guidelines for prescribing antibiotic prophylaxis?

Question 29

What is the antibiotic regimen for prophylaxis

Answer 29

Single Dose - 30-60 mins before Procedure

Question 30

***Antibiotics doses for prophylaxis (Adult, Kid)

Answer 30

Amoxicillin 2g / 50mg/kg
Arithromycin 500 mg / 15 mg/kg
Clarithromycin 500mg
Doxycycline 100 mg / 2.2 mg/kg (<45kg)

Question 31

***Dental procedures need prophylaxis?

Answer 31

all dental procedures that involve manipulation of gingival tissue or the periapical regions of teeth or that perforate the oral mucosa. EX:

• Implant placement
• Extraction of tooth
• Biopsies
• Suture removal
• Subgingival restorations or placement of periodontal dressings
• Periodontal probing
• Scaling and root planning
• Any oral surgeries
• Endodontic therapy beyond apex
• Orthodontic band placement
• Intra-ligamentary (PDL) and intraosseous injections

Question 32

***procedures perforate the oral mucosa?

Answer 32

interventions are typically performed with precision and for specific medical or dental reasons. Ex:
- biopsy, oral surgeries, oral piercing,

Question 33

***Which procedures and events do not need prophylaxis for high risk patients:

Answer 33

• routine ANESTHETIC INJECTION through noninfected soft tissue
  
  • dental radiographs
  • placement of removable prosthodontic or orthodontic appliances
  • adjustment of orthodontic appliances
  • placement of orthodontic brackets
  • shedding of deciduous teeth (tooth exfoliation vs eruption)
• bleeding from trauma to the lips or mucosa

Question 34

*** Antifungal. - the most common ? Dosage

Answer 34

Nystatin suspension
Strength : 100,000 units/unit
Swish and swallow 400,000 - 600,000 units,
7 - 14 days

Question 35

Wirte a prescription for Nystatin

Answer 35

Nystatin 100,000 units/ml oral suspension
Disp: 300ml
Sig: swish and swallow 1 teaspoon QID for 14 days

Question 36

Penicillin V for dental infection
Strength?
Dose (Adult, Kid)
Duration

Question 37

Amoxicillin for dental infection:
Strength?
Dose (Adult, Kid)
Duration

Answer 37

Strength:
125mg, 250mg, 500mg
125/5 ml; 250/5 ml;
Recommend Dose
Adult: 250-500 mg; TID
Peditatric: 7-13 mg/kg, TID
Duration: 5-10 days

Question 38

Azithromycin for dental infection:
Strength?
Dose (Adult, Kid)
Duration

Question 39

Wirte a prescription for Amoxicillin for Prophylaxis for Adult

Answer 39

Amoxicillin 500mg
Disp: 4 tabs
Sig.: take all tabs at once / 30-60 mins before appointment.
Repeat: 2 times ( different appointments)

Question 40

Wirte a prescription for Amoxicillin for Prophylaxis for Kid (20kg)

Answer 40

Amoxicillin 50 mg/kg