Atrial Flagellates pathogenic Flashcards

(70 cards)

0
Q

Habitat of giardia lambia

A

Duodenum
Jejunum
Upper ileum
Upper small intestine

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1
Q

What are synonyms of giardia lambia?

A

Giardia intestinalis
Lambia intestinalis
Giardia duodenalis
Lambia duodenalis

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2
Q

Epidemiology of gardia lambia

A

Most common acquired STD
Worldwide distribution
Prevalence is 6%; 14% under 9 years old
Increase frequency in multiple partner

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3
Q

Transmission of giardia lambia

Most common source of outbreak

A

Water borne

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4
Q

Transmission of giardia lambia

How many cyst the food have to make contaminated?

A

1-10

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5
Q

Transmission of giardia lambia

Homosexual practices

A

Oro-Anal

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6
Q

Giardia lambia also called

A

Traveller’s diarrhea

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7
Q

How many flagella the giardia lambia have?

A

8

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8
Q

Trophozoite G. Lambia

Shape

A

Pyriform or teardrop shaped

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9
Q

Trophozoite G. Lambia

Pyriform or teardrop shaped. Pointed posteriorly with a distinct medial line called

A

Axostyle

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10
Q

Trophozoite G. Lambia

Description

A

Non infective
Baby stage
9-12 um long, 5-15 um wide
Divide by longitudinal binary fission

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11
Q

Trophozoite G. Lambia

Shape,
Dorsal side and ventral side

A

Dorsal- convex

Ventral- concave

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12
Q

Trophozoite G. Lambia

Shape

Anterior and posterior

A

Anterior- round

Posterior- pointed

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13
Q

Trophozoite G. Lambia

Nuclei

A

A pair of ovoidal nuclei, one on each side of midline

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14
Q

Trophozoite G. Lambia

Flagella

A

Arise from the ventral side
3 pairs flowing
1 pair fused

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15
Q

Trophozoite G. Lambia

Movements

A

Slow erratic oscillation or

Falling leaf motility

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16
Q

Cyst G. Lambia

Description

A

Infective

Adult stage

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17
Q

Cyst G. Lambia

Shape

A

Ovoid

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18
Q

Cyst G. Lambia

Nuclei

A

Young cyst - 2 nuclei

Mature cyst- 4 nuclei

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19
Q

Cyst G. Lambia

Flagella

A

Contracted into axonemes

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20
Q

Cyst G. Lambia

Cytoplasm

A

Separated from cyst wall

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21
Q

Cyst G. Lambia

Diagnostic

A

Retracted cytoplasm

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22
Q

Cyst G. Lambia

Resistant to

A

Chlorine and cold water

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23
Q

Gardia lambia

Incubation period

A

1-4 weeks

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24
Gardia lambia Symptomatic in
40% of patients
25
Gardia lambia Pathologic changes in the intestinal wall
1. Flattened tips of villi and shallow crypts 2. Mucosal inflammation 3. Hyperplasia of lymphoid follicles
26
Gardia lambia Cellular changes
Ventral sucking disc Mechanical irritation Malabsorption
27
Gardia lambia Mild infection
Moderate and protracted diarrhea | 6 weeks spontaneous recovery
28
Gardia lambia Acute infection
``` Cramping and diarrhea Exessive flatus ( rotten egg) ``` Bloating, nausea, anorexia more reported than diarrhea
29
Gardia lambia Chronic infection
Steatorrhea Cholecystitis Less diarrhea because pt is already dehydrated
30
Gardia lambia Severe infection
Malabsorption in the gut | Very weak
31
Gardia lambia diagnosis Watery stool
Not accurate
32
Gardia lambia diagnosis Semi formed stool
Best specimen
33
Gardia lambia diagnosis Stool exam
Demonstrate trophozoites or cyst
34
Gardia lambia diagnosis Direct fecal smear
Trophozoites seen as having a falling leaf-like motility
35
Gardia lambia diagnosis Invasive procedure
Duodenojejunal aspiration biopsy
36
Gardia lambia diagnosis May demonstrate trophozoite An expensive test
Entero test
37
Gardia lambia diagnosis Enzyme linked immunosorbent assay using giardia antigen in the stool is a more sensitive method for indentifying giardia
ELISA
38
Gardia lambia treatment Metronidazole
500 mg TID for 5-10 days
39
Gardia lambia treatment Metronidazole Pedriatic dose
15 mg/kg/day in 3 divided dosed | 90% cure rate
40
Gardia lambia treatment Metronidazole Side effect
Metallic taste
41
Gardia lambia treatment Tinidazole
2 g single dose for adults; | 50 mg/kg in children
42
Gardia lambia treatment Furazolidine
100 mg QID for 7-10 days
43
Gardia lambia treatment Furazolidine Pedriatic dose
6 mg/kg/day in 4 diided doses
44
Gardia lambia prevention
Proper and sanitary disposal of excrete to prevent contamination of watery supplt and food Avoidance of night soil as fertilizers, flies and infected food handlers
45
Trichomonas vaginalis
STD
46
Trichomonas vaginalis Habitat
Urogenital tract Vagina, urethra, prostate, epididymis
47
Trichomonas vaginalis Cyst
No cyst form
48
Trichomonas vaginalis Shape
7-23um | Pyriform shape
49
Trichomonas vaginalis Flagella
4 anterior flagella - simple stalk | 5th flagella - undulating membrane, extends about 1/2 of original lenght
50
Trichomonas vaginalis Nucleus
Median axostyle | Sinke nucleus
51
Trichomonas vaginalis Multiply by
Bunary fission
52
Trichomonas vaginalis Transmission
Ping pong infection
53
Trichomonas vaginalis Diagnostic
Cystostome | Siderophil granules
54
Trichomonas vaginalis Aka
Jerky tumbling motility
55
Trichomonas vaginalis Trophozoite cant't live without close association with
Vagina Urethral Prostatic tissue
56
Trichomonas vaginalis Trophozoite infect the surface but do not appear to invade the
Mucosa
57
Trichomonas vaginalis 4-28 days after introduction of the trophozhoite into the vagina
Proliferation of flagella Degenaration of vaginal epithelium Leukocytic inflammation of tissue
58
Trichomonas vaginalis Acute infection
Greenish to yellowish secretion Intense itchiness Burning sensation
59
Trichomonas vaginalis Chronic stage
Loses purulent appearance due to decrease tirchomonads and leukocytes Increase epithelial cells Mixed bacterial flora
60
Trichomonas vaginalis Common symptoms
Vaginal discharge Vulvitis Dysuria Postpartum endometritis
61
Trichomonas vaginalis Complication include secondary bacterial infection of the
Urogenital tract in male
62
Trichomonas vaginalis On speculumexamination, there are punctuate hemorrhages of the cervix
Strawberry cervix
63
Trichomonas vaginalis diagnosis
Collectiin of discharge
64
Trichomonas vaginalis diagnosis From discharges
Saline wet mounts
65
Trichomonas vaginalis diagnosis In males
Prostatic secretions and urine
66
Trichomonas vaginalis diagnosis Culture using
Diamond ( modfied medium ) | Feinberg and whittington culture medium
67
Trichomonas vaginalis treatment
Metronidazole- 500 mg TID for 7 days (90-98% cure rate) Tinidazole-2 mg single dose
68
Trichomonas vaginalis In RP, prevalence rate is
14-8% among sexual workers
69
Tenax Hominis Vaginalis
Oral cavity Large intestine Uro- genital tract