Atropine

Question 1

Class

Answer 1

Anticholinergic agent

Question 2

Mechanism

Answer 2

Inhibits acetylcholine increasing heart rate

Question 3

Indications

Answer 3

Bradycardia with hypotension
Organophosphate poisoning
Nerve agent exposure
RSI in pediatrics
Beta blocker overdose
Calcium channel blocker overdose

Question 4

Contraindications

Answer 4

Tachycardia
Unstable cardiovascular status in acute hemorrhage with myocardial ischemia
Narrow-angle glaucoma
Hypothermic bradycardia

Question 5

Side effects

Answer 5

Tachycardia
Headache/confusion
Palpitations
Dysrythmias 
Blurred vision
Flushed/hot dry skin
Decreased oral secretions

Question 6

What happens if pushed too slowly or given at low doses?

Answer 6

Paradoxical bradycardia

Question 7

Supplied in:

Answer 7

1mg to 10mL
0.1 mg/mL
Prefilled syringes

Question 8

Adult dose

Unstable bradycardia

Answer 8

0.5 mg/kg IV or IO every 3-5 minutes

Maximum: 0.04 mg/kg or 3mg total (6 doses)

Question 9

Pediatric dose

Unstable bradycardia

Answer 9

0.02 mg/kg IV/IO

Minimum: 0.1mg
Maximum single: 0.5mg dose (can repeat once)
Maximum total: 1mg

Question 10

Adult organophosphate poisoning

Answer 10

2-4mg

Question 11

Pediatric RSI

Answer 11

0.01-0.02 mg/kg IV/IO

Minimum: 0.1mg
Maximum: 0.5mg

Question 12

Peak effect

Answer 12

1-2 minutes

Question 13

Duration

Answer 13

2-6 hours

Question 14

Adolescent dose

Unstable bradycardia

Answer 14

0.5mg IV/IO every 3-5 minutes

Minimum dose: 0.1mg
Maximum single: 1mg
Maximum total: 3mg