Auto-Antibodies Flashcards by Megan Buschjost | Brainscape

Q

anti-AChR

A

myasthenia gravis

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Q

anti-presynaptic Ca²⁺ channel

A

lambert-eaton syndrome

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Q

anti-β₂ glycoprotein I

A

antiphospholipid syndrome

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Q

anti-nuclear (ANA)

A

nonspecific; SLE

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Q

anti-cardiolipin

A

SLE

antiphospholipid syndrome

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Q

lupus anticoagulant

A

SLE

antiphospholipid syndrome

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Q

anti-dsDNA

A

SLE

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Q

anti-Smith

A

SLE

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Q

anti-histone

A

drug-induced lupus

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Q

anti-U1 RNP (ribonucleoprotein)

A

mixed connective tissue disease

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Q

rheumatoid factor (IgM Ab against IgG Fc region)

A

rheumatoid arthritis (low specificity)

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Q

anti-CCP

A

rheumatoid arthritis

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Q

anti-Ro/SSA, anti-La/SSB

A

sjögren syndrome

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Q

anti-Scl-70 (anti-DNA topoisomerase I)

A

scleroderma (diffuse)

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Q

anti-centromere

A

scleroderma (limited, CREST syndrome)

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Q

anti-synthetase (anti-Jo-1)

A

polymyositis

dermatomyositis

Q

anti-SRP

A

polymyositis

dermatomyositis

Q

anti-helicase (anti-Mi-2)

A

polymyositis

dermatomyositis

Q

anti-mitochondrial

A

1° biliary cholangitis

Q

anti-smooth muscle

A

autoimmune hepatitis

Q

MPO-ANCA/p-ANCA

A

microscopic polyangiitis

eospinophilic granulomatosis with polyangiitis (Churg-Strauss)

ulcerative colitis

Q

PR3-ANCA/c-ANCA

A

granulomatosis with polyangiitis (Wegener)

Q

anti-phospholipase A₂ receptor (PLA₂R)

A

1° membranous nephropathy

Q

anti-hemidesmosome

A

bullous pemphigoid

Q

anti-desmoglein (anti-desmosome)

A

pemphigus vulgaris

Q

anti-microsomal

A

hashimoto thyroiditis

Q

anti-thyroglobulin

A

hashimoto thyroiditis

Q

anti-thyroid peroxidase (TPO)

A

hashimoto thyroiditis

Q

anti-TSH receptor

A

grave’s disease

Q

IgA anti-endomesial

A

celiac disease

Q

IgA anti-tissue transglutaminase

A

celiac disease

Q

IgA and IgG demainated gliadin peptide

A

celiac disease

Q

anti-glutamic acid decarboxylase

A

type I diabetes mellitus

Q

islet cell cytoplasmic Abs

A

type I diabetes mellitus

Q

anti-parietal cell

A

pernicious anemia

Q

anti-intrinsic factor

A

pernicious anemia

Q

anti-glomerular bsement membrane

A

goodpasture syndrome