Auto-Antibodies Flashcards by Megan Buschjost

Q

anti-AChR

A

myasthenia gravis

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Q

anti-presynaptic Ca²⁺ channel

A

lambert-eaton syndrome

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Q

anti-β₂ glycoprotein I

A

antiphospholipid syndrome

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Q

anti-nuclear (ANA)

A

nonspecific; SLE

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Q

anti-cardiolipin

A

SLE

antiphospholipid syndrome

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Q

lupus anticoagulant

A

SLE

antiphospholipid syndrome

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Q

anti-dsDNA

A

SLE

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Q

anti-Smith

A

SLE

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Q

anti-histone

A

drug-induced lupus

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Q

anti-U1 RNP (ribonucleoprotein)

A

mixed connective tissue disease

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Q

rheumatoid factor (IgM Ab against IgG Fc region)

A

rheumatoid arthritis (low specificity)

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Q

anti-CCP

A

rheumatoid arthritis

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Q

anti-Ro/SSA, anti-La/SSB

A

sjögren syndrome

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Q

anti-Scl-70 (anti-DNA topoisomerase I)

A

scleroderma (diffuse)

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Q

anti-centromere

A

scleroderma (limited, CREST syndrome)

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Q

anti-synthetase (anti-Jo-1)

A

polymyositis

dermatomyositis

Q

anti-SRP

A

polymyositis

dermatomyositis

Q

anti-helicase (anti-Mi-2)

A

polymyositis

dermatomyositis

Q

anti-mitochondrial

A

1° biliary cholangitis

Q

anti-smooth muscle

A

autoimmune hepatitis

Q

MPO-ANCA/p-ANCA

A

microscopic polyangiitis

eospinophilic granulomatosis with polyangiitis (Churg-Strauss)

ulcerative colitis

Q

PR3-ANCA/c-ANCA

A

granulomatosis with polyangiitis (Wegener)

Q

anti-phospholipase A₂ receptor (PLA₂R)

A

1° membranous nephropathy

Q

anti-hemidesmosome

A

bullous pemphigoid

anti-desmoglein (anti-desmosome)

pemphigus vulgaris

anti-microsomal

hashimoto thyroiditis

anti-thyroglobulin

hashimoto thyroiditis

anti-thyroid peroxidase (TPO)

hashimoto thyroiditis

anti-TSH receptor

grave's disease

IgA anti-endomesial

celiac disease

IgA anti-tissue transglutaminase

celiac disease

IgA and IgG demainated gliadin peptide

celiac disease

anti-glutamic acid decarboxylase

type I diabetes mellitus

islet cell cytoplasmic Abs

type I diabetes mellitus

anti-parietal cell

pernicious anemia

anti-intrinsic factor

pernicious anemia

anti-glomerular bsement membrane

goodpasture syndrome