Autoantibodies Flashcards

1
Q

Anti-IgG Ab

A

Rheumatoid arthritis

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2
Q

Anti-citrullinated protein Ab (ACPA)

A

Rheumatoid arthritis

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3
Q

Anti-centromere

A

CREST

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4
Q

Anti-Scl-70/anti-topoisomerase I

A

diffuse scleroderma

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5
Q

Anti-histone

A

drug-induced lupus

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6
Q

Anti-nuclear Ab (ANA)

A

SLE

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7
Q

Anti-Smith

A

SLE

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8
Q

Anti-dsDNA

A

SLE- esp in lupus nephritis

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9
Q

Anti-SSA (Anti-Ro)

A

Sjogren

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10
Q

Anti-SSB (Anti-La)

A

Sjogren

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11
Q

Anti-U1-RNP

A

mixed connective tissue disease

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12
Q

Anti-demoglein

A

pemphigus vulgaris

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13
Q

Anti-ACh R

A

myasthenia gravis

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14
Q

Anti-endomysial (Anti-tissue transglutaminase)

A

Celiac

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15
Q

Anti-gliadin

A

Celiac

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16
Q

Anti-mitochondrial

A

primary biliary cirrhosis

17
Q

Anti-smooth muscle

A

autoimmune hepatitis

18
Q

Anti-glutamate decarboxylase

A

type I diabetes

19
Q

Anti-thyrotropic R

A

Graves

20
Q

Anti-thryoid peroxidase (Anti-TPO)

A

Hashimoto

21
Q

Anti-thyroglobulin

A

Hashimoto or Graves

22
Q

Anti-basment membrane

A

Goodpasture

23
Q

c-ANCA

A

Wegner’s

24
Q

p-ANCA

A

Pauci-immune crescentic glomerulonephritis
Churg-Strauss
Microscopic polyangiitis