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Autoantibodies > Autoantibodies > Flashcards

Autoantibodies Flashcards

1
Q

anti-ACh receptor

A

myasthenia gravis

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2
Q

anti-GBM

A

Goodpasture syndrome

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3
Q

anti-B2 microglobulin

A

anti-PL syndrome

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4
Q

anticardiolipin

A

SLE, anti-PL syndrome

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5
Q

lupus anticoagulant

A

SLE, anti-PL syndrome

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6
Q

anticentromere

A

CREST (limited scleroderma)

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7
Q

anti-desmoglein

A

pemphigus vulgaris

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8
Q

anti-glutamic acid decarboxylase

A

DM1

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9
Q

islet cell cytoplasmic antibodies

A

DM1

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10
Q

anti-hemidesmosome

A

bullous pemphigoid

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11
Q

anti-Jo-1 is against ___ and is found in _____

A

histidyl tRNA synthetase, polymiositis/dermatomycositis

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12
Q

anti-Mi-2 is against _____ and is found in _____

A

helicase, polymyositis/dermatomyositis

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13
Q

anti-SRP

A

polymyositis, dermatomyositis

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14
Q

anti-microsomal

A

Hashimoto thyroiditis

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15
Q

anti-thyroglobulin

A

Hashimoto

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16
Q

anti-TPO

A

Hashimoto

17
Q

antimitochondrial

A

PBC, PSC

18
Q

anti-parietal cell

A

pernicious anemia

19
Q

anti-IF

A

pernicious anemia

20
Q

anti-PLA2 receptor

A

primary membranous nephropathy

21
Q

anti-Scl-70 is against _____ and is found in ______

A

DNA topoisomerase I, diffuse scleroderma

22
Q

anti-smooth muscle

A

autoimmune hepatitis

23
Q

anti-SSA (Ro), anti-SSB (La)

A

Sjogren

24
Q

anti-TSH receptor

A

Graves

25
Q

anti-presynaptic VG Ca+ channel

A

Lambert-Eaton

26
Q

anti-endomysial

A

celiac

27
Q

anti-tissue transglutaminase

A

celiac

28
Q

pANCA (mpo-ANCA)

A

microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis (Churg-Straus), UC

29
Q

cANA (pr3-ANCA)

A

granulomatosis with polyangiitis (Wegener)

30
Q

RF is against ____ and is found in _____

A

Fc portion of IgG, RA

31
Q

anti-CCP

A

RA

32
Q

ANA

A

SLE

33
Q

anti-dsDNA

A

SLE

34
Q

anti-Smith against ___ found in _____

A

snRNPs, SLE

35
Q

anti-histone

A

drug induced SLE (procainamide, dapsone, hydral, INH - slow acetylators)

36
Q

anti-RNP

A

mixed connective tissue dz

Autoantibodies (1 decks)

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