Autoimmune disease Flashcards
(26 cards)
Lead marker for detection of RA
Anti CCP ( cyclic citrullinated peptide)
Antibody most specific for SLE
Anti-ds DNA
Ab specific for lupus associated with uridine rich RNA
Anti- smith (sm)
HLA associated with graves ds
HLA DR3 DR4 DQ
Formation of white plaques in the white matter of the brain and spinal cord, causing the destruction of myelin sheath of axons
Multiple sclerosis
Oligoclonal banding
Multiple sclerosis
Anti acetylcholine
Myesthenia gravis
Auto antibody that usually occurs after viral infection
Good pasteur syndrome
Anti basment antibodies
Good pasteur syndrome
T/F malignant cells undergo apoptosis
F
T/F malignant cells develop into mature cells
F
Most common humoral ab deficiency
Iga deficiency
Deficiency with NO BCELLS
Brutons X linked agammaglobulinemia
Bcells do not differentiate into plasma cells
Common variable deficiency
Catch 22
Di george syndrome
Underdeveloped thymus
Digeorge syndrome
Defect in stemcell maturation
SCID
Deficient adenosine deaminase
Scid
Wasp gene
Wiskott aldrich syndrome
Defect in kinase gene affecting the t & b cell
Ataxia telangiectasia
Defective neutrophil chemotaxis
Jobs/igE deficiency
3 E’s in jobs syndrome
Elevated IgE
Eczema
Eosinophilia
Defect in CD40 ligand = prevents class switching
Hyper IgM syndrome
Defective NADPH oxidase
CGD
