Autonomic Drugs

Question 1

Muscarinic Agonist (M1, M2, M3)
U: Bowel and bladder atony

Answer 1

Betanechol

Question 2

Muscarinic and Nicotinic Agonist

U: Cataracts

Answer 2

Carbachol

Question 3

Muscarinic Agonist (M3)
U: Sjogren Syndrome, Sicca Syndrome

Answer 3

Pilocarpine

Question 4

Nicotinic Agonist

U: Smoking cessation

Answer 4

Varenicline

Question 5

Acetylcholinesterase Inhibitor

U: Tensilon Test

Answer 5

Edrophonium

Question 6

Acetycholinesterase Inhibitor
DOC: Myasthenia Gravis
U: Reversal of Muscle Relaxants; Ogilvie Syndrome

Answer 6

Neostigmine

Question 7

Acetylcholinesterase Inhibitor

U: Alzheimer’s Disease

Answer 7

Rivastigmine

Question 8

Non-selective Muscarinic Antagonist

Hyoscine-N-Butyl-Bromide

Answer 8

Scopolamine

Question 9

Non-selective Muscarinic Antagonist
DOC: Organophosphate Toxicity
SE: Hyperthermia

Answer 9

Atropine

Question 10

Non-selective Muscarinic Antagonist

Shortest DOA

Answer 10

Tropicamide

Question 11

Non-selective Muscarinic Antagonist

U: Bronchial Asthma

Answer 11

Ipratropium, Tiotropium

Question 12

Non-selective Muscarinic Antagonist

U: Urinary incontinence and urgency

Answer 12

Oxybutinin

Question 13

Chemical antagonist of Organophosphates

Given within 6-8 hours post-exposure

Answer 13

Pralidoxime

Question 14

Sympatomimetic (A1, B1, B2)

DOC: Anaphylaxis

Answer 14

Epinephrine

Question 15

Sympatomimetic (A1, B1, B2)

Effect: Alpha > Beta

Answer 15

Norepinephrine

Question 16

Sympatomimetic (A1, B1, D1)

Answer 16

Dopamine

Question 17

Non-selective Beta Agonist

U: Bronchial Asthma

Answer 17

Isoproterenol

Question 18

A1 Agonist
U: Decongestant
SE: Rhinitis Medicamentosa

Answer 18

Phenylephrine

Question 19

A2 Agonist

SE: Rebound Hypertension

Answer 19

Clonidine

Question 20

A2 Agonist
U: Pre-ecclampsia
SE: Hemolytic Anemia

Answer 20

Methyldopa

Question 21

A2 Agonist

U: Glaucoma

Answer 21

Apraclonidine

Brimonidine

Question 22

B1 Agonist

U: Cardiogenic Shock

Answer 22

Dobutamine

Question 23

B2 Agonist

DOC: Bronchial Asthma (Acute)

Answer 23

Salbutamol

Question 24

D1 Agonist

U: Hypertension

Answer 24

Fenoldopam

Question 25

D2 Agonist | U: Hyperprolactinemia, Parkinson's Disease

Answer 25

Bromocriptine

Question 26

Non-selective Alpha Antagonist Irreversible U: Pheochromocytoma

Answer 26

Phenoxybenzamine

Question 27

Non-selective Alpha Antagonist Reversible U: Rebound HPN, Pheochromocytoma

Answer 27

Phentolamine

Question 28

A1 Antagonist | U: Co-existing HPN and BPH

Answer 28

Prazosin Doxazosin Terazosin

Question 29

A1a Antagonist | Prostate-selective

Answer 29

Tamsulosin

Question 30

Non-selective Beta Antagonist A1 Antagonist U: Pheochromocytoma Safe for pregnancy

Answer 30

Labetalol

Question 31

Non-selective Beta Antagonist A1 Antagonist U: Pheochromocytoma Reduces mortality in HF

Answer 31

Carvedilol

Question 32

Non-selective Beta Antagonist | Longest half-life

Answer 32

Nadolol

Question 33

Selective Beta Antagonist Shortest half-life U: SVT, Thyroid Storm

Answer 33

Esmolol

Question 34

Beta Antagonists | Intrinsic Sympatomimetic Activity

Answer 34

Pindolol (Non-selective) | Acebutolol (Selective)

Question 35

Beta Antagonists | No local anesthetic effects

Answer 35

Timolol (Non-selective) | Betaxolol (Selective)

Question 36

Selective Beta Antagonist | Vasodilatory effect

Answer 36

Nebivolol

Question 37

B2 Agonist | U: Tocolytic

Answer 37

Terbutaline

Question 38

Non-selective Muscarinic Antagonist | U: Parkinson's Disease

Answer 38

Benztropine Biperiden Trihexyphenidyl