Autonomic nervous system (Chapter 14) Flashcards

(86 cards)

1
Q

the involuntary arm of the peripheral nervous system, also known as the visceral motor division

A

autonomic nervous system

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2
Q

the autonomic nervous system is divided into what two divisions?

A
  • sympathetic

* parasympathetic

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3
Q

sympathetic and parasympathetic nervous systems; constantly work together to maintain?

A

homeostasis

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4
Q

The ANS oversees most vital functions including

A
  • heart rate
  • blood pressure
  • digestive and urinary processes
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5
Q

What does the autonomic motor division innervate?

A

smooth muscle cells, cardiac muscle cells, and glands; produce involuntary actions

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6
Q

ANS motor neurons do not directly innervate their target cells, they need a two neuron circuit which includes?

A
  • preganglionic neuron

* postganglionic neuron

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7
Q

initial efferent neuron; cell body resides within CNS; all axons release acetylcholine

A

preganglionic neuron

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8
Q

cell body resides in autonomic ganglion in PNS; axons travel to target cells; trigger specific changes (inhibitory or excitatory responses) by releasing either acetylcholine or norepinephrine

A

postganglionic neuron

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9
Q

preganglionic axons are usually short and postganglionic axons are usually long in which division?

A

sympathetic nervous system

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10
Q

preganglionic parasympathetic axons are long while postganglionic axons are short

A

parasympathetic nervous system

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11
Q

Preganglionic cell bodies originate in thoracic and upper lumbar spinal cord giving rise to name

A

thoracolumbar division

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12
Q

generally located near spinal cord, where preganglionic axons synapse with postganglionic neuron cell bodies; postganglionic axons proceed to target

A

sympathetic ganglia

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13
Q

the “fight or flight” division of the ANS, prepares the body for emergency situations

A

sympathetic nervous system

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14
Q
  • Vital role in maintenance of homeostasis when body is engaged in physical work
  • Mediates body’s responses to emotion
A

sympathetic nervous system

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15
Q

Preganglionic cell bodies are located within nuclei of several cranial nerves in brainstem and sacral region of spinal cord giving rise to name

A

craniosacral division (parasympathetic)

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16
Q

innervate structures of head and neck, thoracic viscera, and most abdominal viscera

A

cranial nerves of the parasympathetic nervous system

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17
Q

innervate structures within pelvic cavity

A

sacral nerves of the parasympathetic nervous system

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18
Q

Cell bodies of postganglionic neurons are usually located near target organ; requires only a short axon to make connection

A

parasympathetic nervous system

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19
Q

“Rest and digest” division; role in digestion and in maintaining body’s homeostasis at rest

A

parasympathetic nervous system

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20
Q

where most of postganglionic cell bodies are found; run down both sides parallel with vertebral column (Figure 14.4); “chainlike” appearance

A

sympathetic chain ganglia

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21
Q

Section of chain that extends above thoracic spinal cord terminates in

A

superior cervical ganglion

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22
Q

Section of chain that extends below lumbar spinal cord terminates in

A

inferior sacral ganglion

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23
Q

originate in lateral horns of thoracic and lumbar spinal cord; exit with axons of lower motor neurons via anterior root

A

preganglionic neurons

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24
Q

Preganglionic axons quickly separate from spinal nerve anterior ramus to form a small nerve called

A

the white (myelinated) rami communicantes

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25
Some preganglionic axons pass through chain ganglia without forming synapses; may form synapses with
collateral ganglia located near target organ
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Preganglionic axons that synapse with collateral ganglia near organs of abdominopelvic cavity are components of
splanchic nerves
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how do postganglionic axons exit the ganglia?
as small gray (unmyelinated) rami communicantes; reunite to travel with spinal nerves until they reach their target cells
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bind to specific protein-based receptors embedded in plasma membranes of target cells
neurotransmitters
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neurotransmitter used in excitatory synapses between sympathetic preganglionic axons and postganglionic neurons; postganglionic axons then transmit action potentials to target cell
Acetylcholine (ACh)
30
At synapse with their target cells, postganglionic axons release one of three neurotransmitters:
* ACh, * epinephrine (adrenalin), * or norepinephrine (noradrenalin)
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most frequently utilized neurotransmitter released into synapses between postganglionic axons and target cells
norepinephrine
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Adrenergic receptors bind to?
norepinephrine and epinephrine
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The two major types of adrenergic receptors include?
alpha and beta receptors
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An adrenergic receptor in plasma membranes of smooth muscle cells of many different organs, including blood vessels in skin, GI tract, and kidneys, arrector pili muscles in dermis, and certain organs of genitourinary tract
alpha-1 receptors
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An adrenergic receptor in plasma membranes of preganglionic sympathetic neurons instead of in peripheral target cells
alpha-2 receptors
36
An adrenergic receptor in plasma membranes of cardiac muscle cells, certain kidney cells, and adipose cells
beta-1 receptors
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An adrenergic receptor in plasma membranes of smooth muscle cells lining airways of respiratory tract (bronchioles), and in wall of urinary bladder, skeletal muscle fibers, and cells found in liver, pancreas, and salivary glands
beta-2 receptors
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An adrenergic receptor primarily in adipose cells and smooth muscle cells in walls of digestive tract
beta-3 receptors
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this class of sympathetic receptors binds to acetylcholine
cholinergic receptors
40
What are the two types of cholinergic receptors?
* muscarinic | * nicotinic
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found in sweat glands of the skin
muscarinic receptors
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found in membranes of all postganglionic neurons within sympathetic ganglia and adrenal medullae
nicotinic receptors
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how does alpha-2 receptors differ from the other adrenergic receptor subtypes?
When norepinephrine binds to alpha-2 receptors, axon terminal is hyperpolarized; slows or cancels action potential
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occurs when norepinephrine binds to alpha-1 receptors; decreases blood flow to these organs
constriction of blood vessels serving the digestive, urinary, and integumentary system
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occurs when norepinephrine binds to beta-2 receptors; increases amount of air that can be inhaled with each breath
dilation of bronchioles
46
occurs when norepinephrine binds to beta-2 receptors; increases blood flow; allows for an increase in physical activity
dilation of blood vessels serving the skeletal and cardiac muscles
47
occurs when norepinephrine binds to beta-2 and beta-3 receptors respectively; makes emptying bladder and bowel more difficult during increased physical activity
contraction of urinary and digestive sphincters
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occurs when norepinephrine binds to beta-2 receptors; slows digestion during increased physical activity
relaxation of the smooth muscle of the digestive tract
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occurs when norepinephrine binds to alpha-1 receptors; causes dilator pupillae muscles to contract; causes pupil to allow more light into eye
dilation of the pupils
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occurs when norepinephrine binds to beta receptors on blood vessels serving various glands (like salivary glands); decreases secretion, except in sweat glands
Constriction of blood vessels serving most exocrine glands
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occurs during times of sympathetic activation, nearly all cells, especially skeletal muscle, require higher amounts of ATP
effects on cellular metabolism
52
To assist with the higher energy demand norepinephrine has the following three effects:
1. Beta-3 receptors on adipocytes; triggers breakdown of lipids; releases free fatty acids into bloodstream 2. Beta-2 receptors on liver cells; triggers release of glucose from glycogen and synthesis of glucose from other resources 3. Binds to beta-2 receptors on cells of pancreas; triggers release of hormone glucagon; increases blood glucose levels
53
ACh is released from preganglionic neurons; binds to?
nicotinic receptors on adrenal medulla cells
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ACh stimulates medullary cells to release
norepinephrine and epinephrine into bloodstream
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“Rest and digest” division of ANS | Role in body’s maintenance functions, such as digestion and urine formation
parasympathetic nervous system
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Known as craniosacral division based on association with cranial nerves and pelvic nerves from sacral plexus
parasympathetic nervous system
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associated with oculomotor (CN III), facial (CN VII), glossopharyngeal (CN IX), and vagus (CN X) nerves
parasympathetic cranial nerves
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the main parasympathetic nerves that innervate most thoracic and abdominal viscera
two vagus nerves
59
Branches of the vagus nerves contribute to?
* cardiac * pulmonary * esophageal
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Preganglionic axons in oculomotor (CN III) nerve synapse with
ciliary ganglia
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house cell bodies of sensory neurons and synapse with facial (CN VII) nerve
Submandibular and pterygopalatine ganglia
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make up pelvic nerve component of this division; innervates last segment of large intestine, urinary bladder, and reproductive organs
Parasympathetic sacral nerves
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Sacral nerve branches form?
the pelvic splanchnic nerves, forms plexuses in the pelvic floor
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located in membranes of all postganglionic neurons
nicotinic receptors
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located in membranes of all parasympathetic target cells
muscarinic receptors
66
Parasympathetic activity decreases heart rate and blood pressure Preganglionic parasympathetic neurons travel to heart with vagus nerve (CN X)
effects on cardiac muscle in the parasympathetic nervous system
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effects on smooth muscle cells in the PNS include:
* constriction of the pupil * accommodation of the lens for near vision * constriction of the bronchioles * contraction of the smooth muscle lining the digestive tract * relaxation of the digestive and urinary sphincters * engorgement of the penis or clitoris
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involves CN III, ciliary ganglion, and sphincter pupillae muscle; reduces amount of light allowed into eye
constriction of the pupil
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involves CN III and contraction of ciliary muscle; changes lens to a more rounded shaped
accommodation of the lens for near vision
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involves CN X; reduces air flow through bronchioles
Constriction of bronchioles (bronchoconstriction)
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involves CN X; produces rhythmic contractions called peristalsis; propels food through digestive tract
Contraction of smooth muscle lining digestive tract
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involves CN X and sacral nerves; promotes urination and defecation
Relaxation of digestive and urinary sphincters
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occurs when stimulated by sacral nerves in male or female respectively
engorgement of the penis and the clitoris
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* CN VII stimulation stimulates tear production from lacrimal glands and mucus production from glands in nasal mucosa * CN VII and IX stimulation leads to increased production of saliva from salivary glands * CN X stimulates secretion of enzymes and other products from digestive tract cells
Effects on glandular epithethelial cells
75
What are some side effects of anticholinergic drugs that block the parasympathetic nervous system?
* urinary retention * constipation * dry mouth
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What are some side effects of anticholinergic drugs that activate the parasympathetic nervous system?
constricted airways
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innervate many of same organs where their actions antagonize one another, a condition called dual innervation
both sympathetic and parasympathetic divisions
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refers to fact that neither division is ever completely shut down; constant amount of activity from each division
autonomic tone
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dominates in blood vessels; keeps them partially constricted
sympathetic tone
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dominates in heart; keeps heart rate at an average of 72 beats per minute
parasympathetic tone
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how is homeostasis controlled?
centrally by hypothalamus and brainstem reticular formation; actions carried out by the two divisions of ANS
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regions found in reticular formation that contact hypothalamus; contain neurons that control activity of preganglionic sympathetic and parasympathetic neurons
autonomic centers
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what nerve is associated with crutch paralysis?
radial nerve
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what do nicotinic receptors do to the heart rate for each division?
* increases heart in sympathetic division | * decreases heart rate in parasympathetic division
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what occurs when poison inactivates AChE?
there will be a lot more ACh, enzyme that breaks it down will be missing
86
what happens when agonist activate beta adrenergic receptors?
sympathetic nervous system dilates airways