Autonomic Pharmacology Flashcards

(53 cards)

1
Q

Hemicholinium

A

Inhibitor of choline uptake

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2
Q

Botulin toxin

A

By brevin prevent Ach release in post synaptic

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3
Q

Edrophonium

A

Reversible AchE inhibitor

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4
Q

Physostigmine

A

Reversible AchE inhibitor

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5
Q

Neostigmine

A

Reversible AchE inhibitor

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6
Q

Malathion

A

Irreversible AchE inhibitor - indirect acting cholinomimetics

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7
Q

Parathion

A

Irreversible AchE inhibitor - indirect acting cholinomimetics

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8
Q

Betanechol

A

Muscarinic Agonist; lieus and urinary retention

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9
Q

Methacoline

A

Muscarinic Agonist; bronquial hyper reactivity

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10
Q

Pilocarpine

A

Muscarinic Agonist; xerostomia - glaucoma

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11
Q

Endrophonium

A

Acetylcholinesterase inhibitor; miastenia gravis

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12
Q

Physostigmine

A

Acetylcholinesterase inhibitor; glaucoma- atropine over dose

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13
Q

Neostigmine

A

Acetylcholinesterase inhibitor; ileus- urinary retention- miastenia gravis

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14
Q

Pyridostigmine

A

Acetylcholinesterase inhibitor; ileus - urinary retention- miastenia gravis

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15
Q

Donepezil

A

Acetylcholinesterase inhibitor; Alzheimer

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16
Q

Rivastigmine

A

Acetylcholinesterase inhibitor; Alzheimer

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17
Q

Organophosphates

A

Acetylcholinesterase inhibitor; insecticide- nerve gas ( sarin)

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18
Q

Atropine

A

Muscarinic receptor antagonist - antispasmodic, antisecretory, AchE inhibitor OD, ophthalmology

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19
Q

Tropicamide

A

Muscarinic receptor antagonist; ophthalmology

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20
Q

Ipratropium

A

Muscarinic receptor antagonist; asthma and COPD

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21
Q

Scopolamine

A

Muscarinic receptor antagonist; used in motion sickness

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22
Q

Benztropine

A

Muscarinic receptor antagonist; lipid soluble (CNS entry) used in Párkinsonism and acute extrapyramidal symptoms by antipsychotics

23
Q

Oxybutynin

A

Muscarinic receptor antagonist; overactive bladder (urge incontinence)

24
Q

Hexamethonium

A

Nicotine Receptor Antagonist; Ganglion blocking agents;

25
Mecamylamine
Nicotine Receptor Antagonist; Ganglion blocking agents;
26
Phenylephrine
Direct-Acting Adrenoreceptor Agonist; a1 Agonist. Nasal decongestant and ophthalmologic use. Hypotensive states
27
Clonidine
Direct-Acting Adrenoreceptor Agonist; a2 Agonist. Mild to moderate hypertension
28
Methyldopa
Direct-Acting Adrenoreceptor Agonist; a2 Agonist. Mild to moderate hypertension
29
Isoproterol
Direct-Acting Adrenoreceptor Agonist; B-Agonist. B1=B2
30
Dobutamine
Direct-Acting Adrenoreceptor Agonist; B-Agonist. B1>B2. Congestive heart failure
31
Salmeterol
Direct-Acting Adrenoreceptor Agonist; B-Agonist. Selective B2 - Asthma
32
Albuterol
Direct-Acting Adrenoreceptor Agonist; B-Agonist. Selective B2 - Asthma
33
Terbutaline
Direct-Acting Adrenoreceptor Agonist; B-Agonist. Selective B2 - Asthma
34
Norepinephrine
Mixed-Acting Agonists; a1, a2, B1
35
Ephinephrine
Mixed-Acting Agonists; Low dose: B1 - B2 Medium dose: B1 - B2 - a1 High dose: a1 - B1
36
Tyramine
Indirect-Acting Adrenergic Receptors Agonist; Releasers. MAO-A inhibition
37
Amphetamines
Indirect-Acting Adrenergic Receptors Agonist; Releasers. Psychostimulant due to central release of DA, NE, 5HT
38
Ephedrine
Indirect-Acting Adrenergic Receptors Agonist; Releasers. Cold medication
39
Cocaine
Indirect-Acting Adrenergic Receptors Agonist; Reuptake Inhibitor
40
Tricyclics antidepressant
Indirect-Acting Adrenergic Receptors Agonist; Reuptake Inhibitor
41
Phentolamine
Adrenergic Antagonists - a Receptor Antagonist nonselective blocker (competitive inhibitor)
42
Phenoxybenzamine
Adrenergic Antagonists - a Receptor Antagonist nonselective blocker (non competitive inhibitor)
43
Prazosin
Adrenergic Antagonists - a Receptor Antagonist - selective a1 blocker
44
Doxazosin
Adrenergic Antagonists - a Receptor Antagonist - selective a1 blocker
45
Terazosin
Adrenergic Antagonists - a Receptor Antagonist - selective a1 blocker
46
Tamsulosin
Adrenergic Antagonists - a Receptor Antagonist - selective a1 blocker
47
Mirtazapine
Adrenergic Antagonists - a Receptor Antagonist - selective a2 blocker
48
Acebutolol
Adrenergic Antagonist- B Receptor Antagonist or Beta blockers - B1 selective - ISA
49
Atenolol
Adrenergic Antagonist- B Receptor Antagonist or Beta blockers - B1 selective -
50
Metoprolol
Adrenergic Antagonist- B Receptor Antagonist or Beta blockers - B1 selective -
51
Pindolol
Adrenergic Antagonist- B Receptor Antagonist or Beta blockers - ISA
52
Propranolol
Adrenergic Antagonist- B Receptor Antagonist or Beta blockers - Nonselective - sedation efect
53
Timolol
Adrenergic Antagonist- B Receptor Antagonist or Beta blockers - Nonselective - sedation efect