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FA Pharm > Autonomics - general > Flashcards

Autonomics - general Flashcards

(66 cards)

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1
Q

Alpha1

A

Inc vascular sm contraction, Inc Pupillary dilator muscle constraction (mydriasis), Inc intestinal an bladder sphincter muscle contraction

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2
Q

Inc Vascular sm muscle contraction

A

Alpha1

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3
Q

Inc Pupillary dilator muscle constraction (mydriasis)

A

Alpha1

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4
Q

Inc intestinal an bladder sphincter muscle contraction

A

Alpha1

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5
Q

Alpha2

A

Dec sympathetic tone, Dec insulin release, Dec lipolysis, Inc Platelet Aggregation

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6
Q

Dec sympathetic outflow

A

Alpha2

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7
Q

Dec insulin release

A

Alpha2

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8
Q

Dec lipolysis

A

Alpha2

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9
Q

Inc platelet aggregation

A

Alpha2

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10
Q

Beta1

A

Inc HR, Inc contractility, Inc renin release, Inc lipolysis

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11
Q

Inc HR

A

Beta1

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12
Q

Inc contractility

A

Beta1

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13
Q

Inc renin release

A

Beta1

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14
Q

Inc lipolysis

A

Beta1

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15
Q

Beta2

A

Vasodilation, Bronchodilation, Inc HR, Inc contractility, Inc lipolysis, Inc insulin release, Dec uterine tone (tocolysis), Ciliary muscle relaxation, Inc aqueous humor production

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16
Q

Vasodilation

A

Beta2

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17
Q

Bronchodilation

A

Beta2

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18
Q

Inc HR

A

Beta2

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19
Q

Inc contractility

A

Beta2

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20
Q

Inc lipolysis

A

Beta2

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21
Q

Inc insulin release

A

Beta2

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22
Q

Dec uterine tone (tocolysis)

A

Beta2

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23
Q

Ciliary muscle relexation

A

Beta2

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24
Q

Inc aqueous humor production

A

Beta2

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25
M1
CNS, enteric nervous system
26
M2
Dec HR and contractility of atriia
27
M3
Inc exocrine gland secretion (e.g. lacrimal, salivary, gastric acid), Inc gut peristalsis, Inc bladder contraction, bronchoconstriction, Inc papillary sphincter muscle contraction (miosis), ciliary muscle contraction (accommodation)
28
Inc exocrine glands secretion(lacrimal, salivary, gastric)
M3
29
Inc gut peristalsis
M3
30
Inc Bladder contraction
M3
31
Bronchoconstriction
M3
32
Inc pupillary sphincter muscle contraction (miosis)
M3
33
Cilirary m. contraction (accommodation)
M3
34
D1
Relaxes renal vascular smooth m.
35
Relaxes renal vascular smooth m.
D1
36
D2
Modulates NT release, esp in brain
37
Modulate NT release, esp in brain
D2
38
H1
Inc nasal and bronchial mucus production, Inc vacular permeability, Contraction of bronchioles, pruritus, and pain
39
Inc nasal and bronchial mucus production
H1
40
Inc vascular permeability
H1
41
Contraction of bronchioles
H1
42
Pruritus
H1
43
Pain
H1
44
Inc gastric acid secretion
H2
45
H2
Inc gastric acid secretion
46
V1
Inc vascular smooth muscle contraction
47
V2
Inc H2O permeability and resorption in the CT of kidney
48
Alpha1
Gq
49
Alpha2
Gi
50
Beta1
Gs
51
Beta2
Gs
52
M1
Gq
53
M2
Gi
54
M3
Gq
55
D1
Gs
56
D2
Gi
57
H1
Gq
58
H2
Gs
59
V1
Gq
60
V2
Gs
61
Gq pathway
PLC cleaves PIP2 -> DAG + IP3. DAG -> PKC. IP3 -> Calcium increase -> Smooth Muscle contraction
62
Gq listing
Alpha1, M1, M3, H1, and V1
63
Gs listing
Beta1, Beta2, D1, H2, V2
64
Gi listing
M2, Alpha2, D2
65
Gs pathway
activate AC, cAMP, PKA -> inc Ca + myosin light-chain kinase (smooth muscle)
66
Gi pathway
inhibit AC, cAMP, PKA -> dec Ca2+

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