B&B Motor control Flashcards
(40 cards)
Describe low, middle and high motor control hierarchy
High : Strategy
(what is the goal of movement?)
Association of neocortex, basal ganglia and cerebellum
Medium: Tactics
(Muscle contractions required to achieve the strategic goal)
Motor cortex, cerebellum.
Low: Execution
(Activation of motor neuron and interneuron pools that generate the movement)
Brain stem, spinal cord
What does the Cerebral neocortex provide
information about body positioning in egocentric space
Why can ballistic movements not be altered once initiated?
No sensory feedback
But there is sensory information before the movement is initiated or during the movement.
Sensorimotor transformation = sensory stimuli being converted into motor commands.
It depends on 2 things. What are these?
- Extrinsic information about the world around us – spatial location of a target.
- Intrinsic information about our body – kinematic and kinetic information
Give some examples of kinematic and kinetic information
Kinematic = Position, velocity and acceleration of the hand. Joint angle. Lengths of muscles Kinetic = The forces generated or experienced by the body.
How do sensorimotor transformations generate movement to a desired location?
1) Target is localised in egocentric space (relative to the head)
2) Plan of movement (path and trajectory) and initial location of endpoint and endpoint trajectory.
3) Inverse kinematic transformation. The joint trajectories to achieve the hand path are determined.
4) Inverse dynamic transformation. Joint torques or muscle activities to achieve joint trajectory are determined
What is the motor response?
Stimulation of the primary motor cortex
Neural circuits compute sensorimotor transformations = internal models
Internal models can take 2 forms. What are these?
Forward model
Inverse model
Describe the forward model
1 of 2 internal models
The internal model that represents the relationships between actions and their consequences (the predicted behaviour)
Estimates future sensory inputs based on motor outputs.
Anticipates how the motor system will change as a result of the motor command
Describe the inverse model
1 of 2 internal models
the internal model that calculates motor outputs from sensory outputs (the desired behaviour)
Determines the motor commands that are needed to produce the movements necessary to achieve the desired consequence.
What is the speed accuracy trade off?
A limited ability to move rapidly and accurately at the same time
Subject is required to hit a target perpendicular to the direction in which they move
Each subject starts from three different positions.
Each subject is required to complete the movement within three different times (140,170 or 200ms).
Describe feedforward vs feedback control
Feedforward control is used to reduce the effects of measurable disturbances
Feedforward controller generates a motor command based on the desired state.
The movement is not monitored for errors ie. there is no sensory feedback.
while feedback trim compensates for inaccuracies in the process model, measurement error, and unmeasured disturbances.
What is propioception?
Perception or awareness of body position and movement
Patients who have lost proprioception have difficulty controlling the dynamic properties of their limbs. They make clumsy, uncoordinated and inaccurate movements.
How is locomotion controlled?
Locomotion – using rhythmic and alternating movements of the body or appendages.
eg swimming
Locomotion is controlled automatically at relatively low levels of the CNS without the intervention by higher centres
Flexors and extensors inhibit each other reciprocally, what does this give rise to?
Alternating stepping movements
The motor output for locomotion is produced primarily by the WHAT?
Neuronal system in the spinal cord
Flexors and extensors inhibit each other reciprocally, giving rise to alternating stepping movements
It is divided into 4 phases, what are these?
- Flexion (F)
- First Extension (E1)
- Second extension (E2)
- Third extension (E3)
Describe F, E1, E2, E3
-Flexion (F)
-First Extension (E1)
Occur in the swing phase when the foot is off the ground.
-Second extension (E2)
-Third extension (E3)
Occur during stance when the foot makes contact with the ground.
Describe the stumbling corrective reaction
Sensory receptors in the skin influence walking by detecting obstacles and adjusting stepping to avoid them
In cats: Mild mechanical stimulus applied to dorsal part of the paw in swing phase
Excitation of flexor motor neurons and inhibition of extensor motor neurons.
Rapid flexion of the paw away from stimulus and elevation of the leg to step over object
Describe spinal preparations (acute spinal)
Different preparations are used to study the neuronal control of stepping
Spinal preparation = spinal cord transected at the lower thoracic level.
- Acute spinal preparations – adrenergic drugs such as L-DOPA or nialamide are administered immediately after the transection.
- Elevation of norepinephrine in the spinal cord.
- Spontaneous generation of locomotor activity 30minutes after administration
Describe spinal preparations (chronic spinal) in cats
Different preparations are used to study the neuronal control of stepping
Spinal preparation = spinal cord transected at the lower thoracic level.
- Chronic spinal preparations – transection of the spinal cord, studied for weeks or months.
- Locomotor activity can return within a few weeks of cord transection.
- Locomotor function returns spontaneously in kittens.
- Daily training is required to restore function in adult cats.
What are the 3 descending spinal tracts?
- Corticospinal pathways
- Medial pathways
- Lateral pathways
Describe the corticospinal tract
Functions:
Control of voluntary, discrete and skilled movement.
Distal limbs
Pathway: Arises from motor and sensory cortices. Pass through internal capsule. Enter crus cerebri of the midbrain. Ventral portion of the pons. Medulla oblongata (two prominent columns on dorsal surface = pyramids AKA pyramidal tracts). Fibres decussate: Lateral corticospinal tract (75%-90%)
Describe Hereditary spastic paraparesis
Background:
Inherited degenerative disorder.
Autosomal dominant.
Progressive weakness of the legs.
Increased muscle tone.
Marked stiffness in gait.
Cause:
Degeneration of lateral corticospinal tract.
Chiefly affects thoracic spinal cord
Spastic paraparesis.
