B&B Part 2 Flashcards

1
Q

Senile Plaque

A

Characteristic feature of Alzheimer’s disease.

Composed principally of b-amyloid.

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2
Q

Neurofibrillary tangles

A

ewrew

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3
Q

What is the significance of naming only 6 animals in one minute?

A

rewrw

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4
Q

What is the significance of being able to repeat 2-3 words but not being able to recall them only 1 minute later?

A

rewwer

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5
Q

What is the significance of having difficulty copying a simple geometric design?

A

rwewe

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6
Q

Differential diagnosis for dementia?

A

fda

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7
Q

What are frontal release signs? What is their significance?

A

aasd

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8
Q

What is the pathology of AD?

A

Senile plaques with gliosis.

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9
Q

Which are characteristic microscopic features of AD?

A

Senile b-amyloid plaques
Neurofibrillary tangles
Neuropil threads

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10
Q

Lewy Bodies

A

dasdd

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11
Q

Tau protein

A

A microtubule associated protein that is the principal component of neurofibrillary tangles.

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12
Q

Senile Plaque

A

Characteristic feature of Alzheimer’s disease.

Composed principally of b-amyloid.

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13
Q

Neurofibrillary tangles

A

ewrew

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14
Q

What is the significance of naming only 6 animals in one minute?

A

rewrw

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15
Q

What is the significance of being able to repeat 2-3 words but not being able to recall them only 1 minute later?

A

rewwer

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16
Q

What is the significance of having difficulty copying a simple geometric design?

A

rwewe

17
Q

Differential diagnosis for dementia?

A

fda

18
Q

What are frontal release signs? What is their significance?

A

aasd

19
Q

What is the pathology of AD?

A

Senile plaques with gliosis.

20
Q

Which are characteristic microscopic features of AD?

A

Senile b-amyloid plaques
Neurofibrillary tangles
Neuropil threads

21
Q

Lewy Bodies

A

dasdd

22
Q

Tau protein

A

A microtubule associated protein that is the principal component of neurofibrillary tangles.

23
Q

Frontotemporal lobe dementia (FTD/FTLD)

A

jfkdsn

24
Q

Amyotropic Lateral Sclerosis

A

(ALS)

25
Q

Pick Bodies

A

Tau (microtubule associated protein) inclusions found in FTD.

26
Q

Focal Cortical Dysplasia

A

bjh

27
Q

Where are the venous sinuses formed?

A

In the places where the various leaves of the dura mater come together.

28
Q

Potential space

A

Anatomic term for a space that doesn’t exist under normal conditions, but can be readily created under the appropriate conditions (i.e. pneumothorax, subdural hematoma)

29
Q

What is the most common cause of an epidural hematoma?

A

Rupture of the middle meningeal artery due to trauma, fractured temporal bone.

30
Q

What is a common cause of a subdural hematoma?

A

Tearing of the bridging veins that traverse the subdural space as they pass between the cortical surface and the overlying dura.

This hematoma fills up the potential subdural space.

31
Q

What is contained in the subarachnoid space?

A

Vascular structures (cerebral arteries) + CSF

Full of arachnoid trabeculae

32
Q

Virchow-Robins Space

A

Space that surrounds the vessels within the brain.

It is formed because the pia is tightly attached to the brain, and when it follows the vessels into the brain parenchyma, so does the subarachnoid space.

33
Q

Protoplasmic astrocyte

A

Found mostly in grey matter

Numerous short, highly branched processes

34
Q

Fibrous astrocytes

A

Found mostly in white matter

Fewer and relatively straight processes

35
Q

What is the neuropil?

A

Fibrillary feltwork of projections that arise from and converge on neurons (axons + dendrites) and glial cells

(how they communicate with each other)

36
Q

GFAP

A

Glial fibrillary acidic protein

Intermediate filament found in abundance in astrocytes.

Immunohistochemistry for GFAP is useful for visualizing astrocytic processes as well as for determining whether a glial cell is an astrocyte.