B17 Inherited change Flashcards

1
Q

What is a gene

A

A sequence of bases on a DNA molecules that codes for a protein which results in a characteristic

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2
Q

What is an allele

A

A different version of a gene

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3
Q

What is the definition of genotype

A

The genetic constitution of an organism

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4
Q

What is the definition of phenotype

A

The expression of the genotype and its interaction with the environment

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5
Q

Dominant allele

A

An allele whose characteristic is always expressed even if there is 1

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6
Q

Recessive allele

A

An allele that is only observed in the phenotype if 2 copies are present

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7
Q

Co dominant alleles

A

When both types of alleles are expressed in the phenotype

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8
Q

Locus definition

A

A fixed position of a gene on a chromosome

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9
Q

Homozygote

A

An organism carrying 2 copies of the same allele

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10
Q

Heterozygote

A

An organism carrying 2 copies of different alleles

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11
Q

Monohybrid inheritance

A

Inheritance of a characteristic controlled by 1 single gene

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12
Q

Genetic diagram for monohybrid inheritance of 2 homozygous parents for dominant and recessive

A

Check online lol

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13
Q

What is the F1 generation/ offspring

A

The first set of offspring

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14
Q

F2 offspring

A

I think it’s crossing over the F1 offspring

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15
Q

Ratio of heterozygous dihybrid cross

A

9:3:3:1

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16
Q

Ratio of heterozygous dihybrid cross

17
Q

What makes a sex linked characteristic

A

Allele coding for a characteristic is located on a sex chromosome

18
Q

Is Y smaller than X

19
Q

Why do males more often get recessive linked diseases

A

Males are XY
Females are XX
So males only require 1 recessive allele for it to be expressed whilst females require 2

20
Q

Autosome definition

A

Any chromosome that is not a sex chromosome

21
Q

Where are autosomal genes located

A

On the autosomes

22
Q

Why are genes on the same autosome said to be linked

A

They will not be separated by independent segregation, only can be split up by crossing over.

23
Q

The closer together the 2 genes are on the autosome the more closely they are to be linked because

A

Crossing over is less likely to split them up

24
Q

Why won’t you obtain expected phenotypic ratio for autosomally linked genes?

A

The gametes produced will be limited to the pair that are linked. Therefore a higher proportion of offspring will have their parents genotypes

25
What is epistasis
When the allele of 1 gene masks the expression of an allele of a different gene
26
Dihybrid cross with a recessive epistastic allele ratio
9:4:3
27
Dihybrid cross with a dominant epistastic allele ratio
12:3:1
28
What is the null hypothesis
That there’s no significant difference between the observed and expected values
29
If X^2 is larger than the critical value then
There is a significant difference So we reject the null hypothesis
30
If X^2 is smaller than the critical value
There is no significant difference We can accept the null hypothesis
31
Why is Chi Squared used
Categorical data
32
Autosomal linkage exam question when u compare values
Z individual produced mainly GN and gn gametes. Crossing over produces few Gn or gN gametes. So less Ggnn or ggNn individuals
33
Why don’t the X and Y chromosome form the typical bivalent as other chromosomes do
Y and X are different sizes so the chromatids are unable to line up and form the bivalent shape