B4.033 - Respiratory System Flashcards

(54 cards)

1
Q

what is the function of the respiratory system

A

proveds a system for absorption of atmospheric oxygen into the blood vascular supply, and excretion of CO2 in to the atmosphere

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2
Q

what 4 things does the respiratory system help facilitate

A

Sense of smell

speech

acid-base balance

body temperature control

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3
Q

what are basal cells

A

esentially stem cells, mitotically acitve and produce neuronal cells throughout life

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4
Q

how long do neuronal cells live

A

30-60 d

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5
Q

describe neuronal cells

A

the apical region of neuronal cells faces mucosal surface; contains several modified cilia

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6
Q

how does olfaction work

A

an axonal projection extends from the basal region of neuronal cells and contacts neurons of the olfactory bulb in brain. Oflactory glands secrete a serous fluid containing odorant biding protein which binds to oderant molecules on surface of modified cilia. Secretions also contain lysozyme and secretory IGA.

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7
Q

identify what each arrow is pointitg to

A
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8
Q

what is the conduction system

A

component of respiratory system

Transports inspired and expired gases into and out of the lungs (nasal an oral cavities to trminal bronchioles)

* NO gas exchange

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9
Q

what is the respiration system

A

interface for passive exchange of gases with blood pulmonary acini consisting of respiratory bronchioles, alveolar ducts, alveolar sacs, and avleoli)

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10
Q

what makes up the conducting system and the respiration system

A

conduction system: from teh nasal/oral cavities to the terminal bronchioles, inclusive.

Respiration system: Respiratory bronchiole, avleioli (gas exchange)

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11
Q

what does the pulmonary vein do

A

transports oxygenated blood back to the heart.

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12
Q

what does the pulmonary artery do

A

transports deoxygenated blood

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13
Q

what does the bronchial artery do

A

carry oxygenated blood, also follow the bronchial tree and supply branches to the wallls of the bronchi, arteries, veins and onnectinve tissue septa.

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14
Q

what is the deep (pulmonary) lymphatic plexus do

A

found around bronchi and bronchioles, blood vessels and septa. Links to the superficial lymphatic plexus and also drains into the hylum into main lymphatic vessels

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15
Q

identify what the arrows are pointing to

A
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16
Q

what are the black dots

A
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17
Q

identify where this slide is from and what each layer is

A
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18
Q

what is depicted here

A
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19
Q

what part of the respiratory system has mucous secretion

A

conduction system

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20
Q

where does the cartilage stop in the respiratory system

A

bronchioles, there is no cartilage here

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21
Q

what do 1, 2, 3 represent

A
  1. as bronchi become smaller, irregular cartilage plates are observed. The cartilage plates are surrounded by connective tissue fibers
  2. Bundles of smooth muscle fibers
  3. seromucous glands are observed in lamina propria with secretory acinin projecting beyond the layer of smooth muscle
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22
Q

what is depicted here

A

Motile cilia on apical surface of epithelial cells

no mucus pictured here

goblet cells (non ciliated)

Cilia

23
Q

what is the purpose of mucus

A

mucus protects the lung through mucociliary clearance of dust and othe small particulates, chemicals, and pathogens entering the lung.

24
Q

what is mucus made of

A

water, ions. and various macromolecules, some of which possess protective functions such as anti-microbial, anti-protease, and anti-oxidant activity

25
what do goblet cells do
secrete mucus
26
what provides structural support in the airways to help them stay open
cartilage and smooth muscle
27
what does mucus do
traps gunk you dont want in your lungs and moves it back up to be spit out or swallowed
28
where does the mucus usually lay
on top of the motile cilia
29
what does cigarette smoking do with cilia
affects cilia, metaplasia happens and they dont beat as long or as rhythmically leading to cough and prevents ability to move things out
30
what is the ciliary system called
mucociliary escalator
31
identify structures in black
32
why are there no mucus secreting glands below terminal bronchus
its hard to have gas exchange in an area with lots of mucus
33
what is represented by the M and what are the open areas to the right
smooth muscle alveoli
34
what is represented by each letter
T - terminal bronchus R - respiratory bronchus A - alveoli AD - alviolar duct sacs
35
what are clara/club cells
surfactant secreting cells decrease surface tension to prevent sacs from collapsing during exhaling
36
describe clara cells
apical region of clara cells contains cytoplasmic dense secretory granules, mitochondria and numerous vesicles
37
what ions do clara cells regulate
chloride
38
what is IRDS caused by
lack of surfactant
39
are clara cells ciliated
no
40
where are club cells found
terminal and respiratory bronchioles
41
what are the 4 cell types in the alveoli
Type 1 pneumocyte (alveolar epithelial cell) Type 2 pneumocyte Alveolar macrophage capillary edothelium
42
what is a type 1 pnuemocte
alveolar epithelial cell thin cell, cytoplasm super thin
43
which cell type covers the largest surface area lining the lumen
type 1 pneumocyte
44
what is a type 2 pneumocyte
taller, granulous cell that secretes surfactant
45
how are type 2 pneumocytes different from club cells
secrete a lot more surfactant and have more granules in cytoplasm
46
what is an alveolar macrophage
phagocytoses and degrades old surfactant or infectous material not caught upstream
47
Identify each cell type in this picture
bottom - alveolar endothelial cell
48
what are the most prevalent cell type in the septae of the alveoli
alveolar endothelial cells
49
identify type 1 and type 2 pneumocytes from this drawing
50
P1 - type 1 pneumocyte P2 - type 2 pneumocyte M - macrophage C - capillaries lined by endothelial cells
51
identify the alveolar cells, basal laminae and capillary endothelial cell
left - type 1 alveolar middle - basal laminae right - capillary endothelial cell
52
what cell type is this
Type 2 alveolar cell Surfactant secreting
53
what is silicosis
fibrosis of the lung due to excess silica inducing macrophages to release chemical agents
54
what are these
surfactant granules in type 2 pneumocytes